The Welpr Rating is determined by a scoring formula. The formula takes into account the products safety, user satisfaction, and eco-ethical standing. Click here to learn more.

Welpr Approved cleaning products are always free from:

  • Harsh disinfectants and irritants: bleach, ammonia, sulfates, and quats
  • Endocrine disruptors and preservatives: phthalates, parabens, BHA/BHT, triclosan
  • Unnecessary additives: optical brighteners, artificial dyes, and synthetic fragrance (unless certified safe)
  • Undisclosed or hidden ingredients

View our full standards here.

Our Methodology and Ratings

Find Non-Toxic Oven Cleaner

The Concentrate - Branch Basics

The Concentrate - Branch Basics
Welpr Rating
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Welpr rating icon
5
/5
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Certifications

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<p>This product is <a href="https://www.welpr.com/certifications#welpr-approved" target="_blank">Welpr Approved</a>, meaning it has been vetted against our <a href="https://www.welpr.com/how-we-vet-products/cleaning" target="_blank">cleaning product standards</a> and contains no ingredients from our no list.</p>
<p>Products rated <a href="https://www.welpr.com/certifications#ewg" target="_blank">EWG-A</a> contain minimal health hazards and provide excellent ingredient disclosure. EWG ratings may change. Check the source for most up to date rating. <a href="https://www.ewg.org/cleaners/products/6524-BranchBasicsTheConcentrateFragranceFree/" target="_blank">Source</a>.</p>
<p>The <a href="https://www.welpr.com/certifications#made-safe" target="_blank">Made Safe certification</a> ensures that products are free from harmful chemicals and prioritize human health and ecosystem safety. <a href="https://madesafe.org/products/branch-basics-the-concentrate?_pos=3&_sid=bc8f6f54f&_ss=r" target="_blank">Source</a>.</p>
<p>The <a href="https://www.welpr.com/certifications#leaping-bunny" target="_blank">Leaping Bunny certification</a> assures that products are genuinely cruelty-free, verified through rigorous audits and a comprehensive Supplier Monitoring System.</p>

Highlights

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This product does not contain Bisphenol S (BPS), a common BPA replacement used in plastics with similar health risks.
This product is free from heavy metals like lead and cadmium, which can build up in the body and are linked to developmental, reproductive, and organ toxicity.
This product is free from harsh sulfates like SLS and SLES, which can strip skin and scalp and trigger irritation.
This brand uses sustainable packaging to reduce waste and environmental impact.
This product is free from synthetic dyes that may irritate skin or cause behavioral issues.
This product does not contain Bisphenol F (BPF), a lesser-known BPA replacement used in plastics with similar hormone-disrupting effects.
This product is free from phthalates, a type of plasticizer linked to hormone disruption and reduced fertility.
This product is free from formaldehyde and formaldehyde-releasing agents, preservatives that release toxic gas linked to cancer, allergies, and skin irritation.
This product does not contain Bisphenol A (BPA), a plastic chemical linked to hormone disruption. BPA-free is a good start, but alternatives like BPS and BPF can be just as harmful, so we call those out too.
This product is low-to-free of VOCs, chemicals that off-gas into the air and contribute to indoor air pollution, headaches, and respiratory irritation.
This product is free from chlorine, a respiratory irritant often found in cleaning and bleaching agents.
This product does not contain PFAS, a group of forever chemicals used to make things nonstick, stain-resistant, or waterproof. That includes PTFE, PFOA, and thousands of other compounds linked to hormone disruption and long-term health risks.
This product is free from parabens, a class of preservatives linked to hormone disruption and breast cancer.
This product is free from all fragrance.

User Satisfaction

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We only include products on Welpr that are the best of the best. An EXCELLENT user satisfaction score indicates the product is in the top third of the best products.
Est. Price
$55.00
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Product Details

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  • Effectively cleans surfaces, laundry, dishes, grout, and tough stains.
  • Refillable formula promotes sustainability and reduces waste.
  • Safe plant and mineral-based formula free from harmful chemicals.
  • Certified non-irritating, suitable for sensitive skin and safe for pets.
  • Customizable mixing ratios for various cleaning needs.

Pros & Cons

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Pros

  • Non-toxic and safe, making it ideal for homes with allergies or sensitivities.
  • Versatile application for various cleaning needs like glass, countertops, and laundry.
  • Fresh, mild scent that doesn't overpower your living space.
  • Long-lasting concentrate provides excellent value and reduces waste.
  • Easy to use with clear dilution instructions for effective results.

Cons

  • Some users note it may streak if not properly diluted, particularly on certain countertop surfaces.

Ingredients

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Ingredients: Purified Water, Decyl Glucoside, Organic Chamomile Flower Extract, Coco-Glucoside, Sodium Citrate, Sodium Bicarbonate, Sodium Phytate

Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.

Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.

User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.

Powder Cleanser for Kitchens & Bathrooms, Unscented - Bon Ami

Powder Cleanser for Kitchens & Bathrooms, Unscented - Bon Ami
Welpr Rating
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Welpr rating icon
4.9
/5
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Certifications

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<p>This product is <a href="https://www.welpr.com/certifications#welpr-approved" target="_blank">Welpr Approved</a>, meaning it has been vetted against our <a href="https://www.welpr.com/how-we-vet-products/cleaning" target="_blank">cleaning product standards</a> and contains no ingredients from our no list.</p>
<p>Products rated <a href="https://www.welpr.com/certifications#ewg" target="_blank">EWG-A</a> contain minimal health hazards and provide excellent ingredient disclosure. EWG ratings may change. Check the source for most up to date rating. <a href="https://www.ewg.org/guides/cleaners/213-BonAmiPowderCleanser/" target="_blank">Source</a>.</p>

Highlights

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This product is free from harsh sulfates like SLS and SLES, which can strip skin and scalp and trigger irritation.
This product is free from synthetic dyes that may irritate skin or cause behavioral issues.
This product is free from phthalates, a type of plasticizer linked to hormone disruption and reduced fertility.
This product is free from formaldehyde and formaldehyde-releasing agents, preservatives that release toxic gas linked to cancer, allergies, and skin irritation.
The Made in USA label indicates that a product has substantial U.S. content and manufacturing.
This product is free from chlorine, a respiratory irritant often found in cleaning and bleaching agents.
This product is free from parabens, a class of preservatives linked to hormone disruption and breast cancer.
This product is free from all fragrance.

User Satisfaction

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We only include products on Welpr that are the best of the best. An EXCELLENT user satisfaction score indicates the product is in the top third of the best products.
Est. Price
$7.06
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Product Details

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  • Hypoallergenic and gentle on the skin.
  • Non-toxic and biodegradable for an eco-friendly clean.
  • Cleans without scratching surfaces, protecting your home.
  • Free from chlorine, perfume, and dyes for safer cleaning.
  • Effectively absorbs odors to keep spaces smelling fresh.

Pros & Cons

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Pros

  • Cleans effectively without any toxic chemicals or odors.
  • Gentle on surfaces, doesn't scratch which makes it suitable for sinks and cookware.
  • Versatile for kitchen and bathroom use, removing tough stains effortlessly.
  • Safe for those with sensitivities to chemicals and fragrances.
  • Ingredients are fully listed, offering transparency and peace of mind.

Cons

  • Some users experienced damaged packaging during delivery, which may be a hassle to replace.
  • A bit of effort is required for removing thicker mineral deposits.

Ingredients

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Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.


To analyze individual ingredients, use this EWG tool.


Ingredients: Calcium Carbonate (Limestone), Feldspar Powder, Sodium Carbonate (Soda Ash), Sodium Bicarbonate (Baking Soda), C10-C16 Alkylbenzene Sulfonic Acid (Surfactant)

Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.

Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.

User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.

Multi-Purpose Cleaner, Disinfectant & Deodorizer, Unscented - Force Of Nature

Multi-Purpose Cleaner, Disinfectant & Deodorizer, Unscented - Force Of Nature
Welpr Rating
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Welpr rating icon
4.9
/5
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Certifications

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<p>This product is <a href="https://www.welpr.com/certifications#welpr-approved" target="_blank">Welpr Approved</a>, meaning it has been vetted against our <a href="https://www.welpr.com/how-we-vet-products/cleaning" target="_blank">cleaning product standards</a> and contains no ingredients from our no list.</p>
<p>The <a href="https://www.welpr.com/certifications#epa-registered" target="_blank">EPA Registered certification</a> confirms that a pesticide, including disinfectants, has undergone rigorous evaluation and meets stringent federal standards for safety and effectiveness. <a href="https://ordspub.epa.gov/ords/pesticides/f?p=PPLS:8:::::P8_PUID,P8_RINUM:524191,93040-1" target="_blank">Source</a>.</p>
<p>The <a href="https://www.welpr.com/certifications#green-seal-certified" target="_blank">Green Seal certification</a> signifies that a product has been rigorously evaluated against strict environmental and health standards, ensuring it meets high benchmarks for sustainability and safety. <a href="https://certified.greenseal.org/product/force-of-nature-multi-purpose-cleaner-disinfectant-hci-cleaning-products-force-of-nature" target="_blank">Source</a>.</p>
<p>The <a href="https://www.welpr.com/certifications#clean-label-project" target="_blank">Clean Label Project certification</a> shows a product exceeds basic safety standards and is tested free from the following contaminants: </p>
<p>The <a href="https://www.welpr.com/certifications#carbon-neutral" target="_blank">CarbonNeutral certification</a> confirms that a business has achieved true carbon neutrality.</p>
<p>The <a href="https://www.welpr.com/certifications#leaping-bunny" target="_blank">Leaping Bunny certification</a> assures that products are genuinely cruelty-free, verified through rigorous audits and a comprehensive Supplier Monitoring System.</p>

Highlights

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This product is free from heavy metals like lead and cadmium, which can build up in the body and are linked to developmental, reproductive, and organ toxicity.
This product is free from harsh sulfates like SLS and SLES, which can strip skin and scalp and trigger irritation.
This product is free from synthetic dyes that may irritate skin or cause behavioral issues.
This product is free from phthalates, a type of plasticizer linked to hormone disruption and reduced fertility.
This product is free from formaldehyde and formaldehyde-releasing agents, preservatives that release toxic gas linked to cancer, allergies, and skin irritation.
This product is low-to-free of VOCs, chemicals that off-gas into the air and contribute to indoor air pollution, headaches, and respiratory irritation.
This product is free from chlorine, a respiratory irritant often found in cleaning and bleaching agents.
This product does not contain PFAS, a group of forever chemicals used to make things nonstick, stain-resistant, or waterproof. That includes PTFE, PFOA, and thousands of other compounds linked to hormone disruption and long-term health risks.
This product is free from parabens, a class of preservatives linked to hormone disruption and breast cancer.
This product is free from all fragrance.

User Satisfaction

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We only include products on Welpr that are the best of the best. An EXCELLENT user satisfaction score indicates the product is in the top third of the best products.
Est. Price
$77.40
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Product Details

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  • Kills 99.9% of germs, viruses, and bacteria using a natural process.
  • Replaces multiple cleaners, effective for kitchen, bathroom, glass, and more surfaces.
  • Toxin-free with no added fragrances, dyes, or irritants, safe for all family members.
  • Sustainable design with recyclable capsules, significantly reducing plastic waste.
  • No gloves or rinsing required, ideal for use on baby and pet toys.

Pros & Cons

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Pros

  • Non-toxic and safe for pets and children.
  • Versatile cleaner for various surfaces including upholstery and bathrooms.
  • Leaves a mild, pleasant scent without harsh chemical odors.
  • Easy to use and effective in disinfecting.
  • Eco-friendly option that reduces the need for multiple cleaning products.

Cons

  • Some users experienced issues with the spray bottle breaking.
  • A few customers mentioned the machine may malfunction over time.

Ingredients

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Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.


To analyze individual ingredients, use this EWG tool.


Ingredients: Water, Salt, Vinegar

Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.

Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.

User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.

Save 20% on purchases on Rustic Strength.

Epic Washing Soda, Unscented - Rustic Strength

Epic Washing Soda, Unscented - Rustic Strength
Welpr Rating
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Welpr rating icon
4.8
/5
Discount Code
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WELPR20
Buy Now
on Rustic Strength

Certifications

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<p>This product is <a href="https://www.welpr.com/certifications#welpr-approved" target="_blank">Welpr Approved</a>, meaning it has been vetted against our <a href="https://www.welpr.com/how-we-vet-products/cleaning" target="_blank">cleaning product standards</a> and contains no ingredients from our no list.</p>

Highlights

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This product is free from harsh sulfates like SLS and SLES, which can strip skin and scalp and trigger irritation.
This brand uses sustainable packaging to reduce waste and environmental impact.
This product is free from synthetic dyes that may irritate skin or cause behavioral issues.
This product is free from phthalates, a type of plasticizer linked to hormone disruption and reduced fertility.
This product is free from formaldehyde and formaldehyde-releasing agents, preservatives that release toxic gas linked to cancer, allergies, and skin irritation.
The Made in USA label indicates that a product has substantial U.S. content and manufacturing.
This product is gluten free, and therefore safe for those with celiac or gluten sensitivity.
This product is free from chlorine, a respiratory irritant often found in cleaning and bleaching agents.
This product is free from parabens, a class of preservatives linked to hormone disruption and breast cancer.
This product is free from all fragrance.
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Est. Price
$15.00
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Product Details

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  • Whitens and brightens fabrics and surfaces without harsh chemicals.
  • Neutralizes odors and helps deodorize laundry, bathrooms, and kitchens.
  • Versatile cleaner for laundry, cookware, tile, toilets, carpets, and more.
  • Fully biodegradable and safe for people and the planet when used as directed.
  • Free from dyes, perfumes, sulfates, parabens, phthalates, and other harmful ingredients.

Pros & Cons

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Pros

  • Cleans dishes thoroughly without film, residue, or the need for pre-washing.
  • Safe, non-toxic ingredients provide peace of mind for health-conscious households.
  • Leaves pans, glasses, and silicone items sparkling clean.
  • Fresh peppermint scent adds a natural, pleasant touch to laundry.
  • Charming packaging that’s both functional and giftable.

Cons

  • May be priced slightly higher than conventional cleaners, but many find the safety and quality worth it.

Ingredients

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Ingredients: 100% Sodium Carbonate

Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.

Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.

User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.

Oven Scrub Cleaner, Unscented - Everneat

Oven Scrub Cleaner, Unscented - Everneat
Welpr Rating
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Welpr rating icon
4.75
/5
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Certifications

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<p>This product is <a href="https://www.welpr.com/certifications#welpr-approved" target="_blank">Welpr Approved</a>, meaning it has been vetted against our <a href="https://www.welpr.com/how-we-vet-products/cleaning" target="_blank">cleaning product standards</a> and contains no ingredients from our no list.</p>
<p>The <a href="https://www.welpr.com/certifications#leaping-bunny" target="_blank">Leaping Bunny certification</a> assures that products are genuinely cruelty-free, verified through rigorous audits and a comprehensive Supplier Monitoring System.</p>

Highlights

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This product is free from harsh sulfates like SLS and SLES, which can strip skin and scalp and trigger irritation.
This product is free from synthetic dyes that may irritate skin or cause behavioral issues.
This product is free from phthalates, a type of plasticizer linked to hormone disruption and reduced fertility.
This product is free from formaldehyde and formaldehyde-releasing agents, preservatives that release toxic gas linked to cancer, allergies, and skin irritation.
The Made in USA label indicates that a product has substantial U.S. content and manufacturing.
This product is free from chlorine, a respiratory irritant often found in cleaning and bleaching agents.
This product is free from parabens, a class of preservatives linked to hormone disruption and breast cancer.
This product is free from all fragrance.

User Satisfaction

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We only include products on Welpr that are the best of the best. A GREAT user satisfaction score indicates the product is in the middle third of the best products.
Est. Price
$25.99
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Product Details

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  • Formulated with high-activity enzymes and plant-derived surfactants to digest grease and carbon buildup.
  • Non-toxic and fragrance-free, making it safe for use in food prep areas and around children and pets.
  • Professional-grade cleaner suitable for ovens, grills, air fryers, bathtubs, and grout.
  • Certified vegan, cruelty-free, and 90% biodegradable for an eco-friendly cleaning experience.

Pros & Cons

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Pros

  • Effectively cleans ovens without strong chemical odors, making it great for sensitive noses.
  • No fumes, ensuring a safer cleaning experience and a pleasant aroma.
  • Tackles tough stains and grime, leaving appliances looking almost new.

Cons

  • Some users noted that it could require considerable scrubbing effort, especially for heavier build-ups.
  • A few mentioned persistent minor stains which might need additional treatments.

Ingredients

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Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.


To analyze individual ingredients, use this EWG tool.


Ingredients: Sodium Bicarbonate, Pumice Stone, Sodium Carbonate, Calcium Carbonate, Water, Isopropylidene Glycerol (Glycerine Derived), Alkyl Polyglucoside, Sodium Citrate, Citric Acid, Glycerine, Xantham Gum

Our Product Rating System

Our Product Rating System

First, Camille (co-creator of Welpr) hand picks cleaner product options from a variety of sources.

Next, we collect information about each product's safety, consumer satisfaction, and eco-ethical standing.

Finally, we run all this information through an algorithm that calculates the Welpr Rating.

Welpr Rating:

5.0/5

The Welpr Rating takes into account 3 things:

  1. Product Safety
  2. Consumer Satisfaction
  3. Ethics & Environment
Product safety

Part 1: Product safety

We evaluate safety information from 3rd party organizations (e.g. EWG, Made Safe, etc.). Instead of relying solely on any one of these companies for safety information, we assess all of them.

Consumer satisfaction

Part 2: Consumer satisfaction

We scour the web for consumer ratings and reviews to verify products are not only cleaner options, but also effective. Products can either be Above Average, Average, or Below average for their respective category (e.g. cleaning products).

Ethics & Environment

Part 3: Ethics & Environment

When you buy a product, you’re supporting that company with your dollars. We believe it’s important to support ethical companies, so we pool together certifications that verify a company's ethics and environmental impact.

Common Harmful Chemicals in Oven Cleaner

Chemical Name

Why it’s harmful

Butoxydiglycol

Diethylene glycol ethers is a chemical that has been found to have hematologic, liver, and kidney effects. Exposure to large amounts, about 250 mg/kg/day, can lead to central nervous system depression and other organ damage in rats and may decrease red blood cell counts. It does not show genotoxic, mutagenic, liver, kidney, blood, or reproductive toxicity in animals or humans, but it is classified as an exceptional allergen. The material can be absorbed through the skin and is identified as a mild skin irritant and a severe eye irritant. Notably, its toxicity is lower than that of ethylene glycol ethers.

Sodium Hydroxide

Sodium hydroxide, also known as caustic soda or lye, is an odorless white crystalline solid that absorbs moisture from the air. It generates significant heat when dissolved in water or neutralized with acid which may ignite combustible materials. It is highly corrosive and is typically used as a solid or in a 50% solution. Sodium hydroxide is used to manufacture a variety of products including soaps, rayon, paper, explosives, dyestuffs, and petroleum products. Exposure to this substance may cause severe burns, necrosis, and pulmonary edema, depending on the concentration and exposure method.

Ammonium Hydroxide

Ammonium hydroxide is a corrosive substance that can cause injury to the skin, eyes, and respiratory tract. High concentrations, either through inhalation or prolonged exposure, can lead to significant respiratory issues, including inflammation, pneumonia, and pulmonary edema. It is used in various industries such as fertilizers, dyes, explosives, plastics, and cleansing agents, among others. Due to its intense pungency and potential to cause extreme irritation and even life-threatening conditions, precautions such as wearing protective clothing and immediate cleansing of affected areas are recommended. It should be stored away from combustibles and heavy metals, in well-ventilated areas and in specified containers. Disposal guidelines also need to be referred from environmental regulatory agencies due to the hazardous nature of the substance.

Sulfuric Acid

Sulfuric acid, a clear and highly corrosive liquid, is employed in the creation of fertilizers, other acids, and glue, and is used in petroleum purification, metal pickling, and lead-acid batteries. It can cause severe burns, is a potential human carcinogen, can trigger pulmonary edema, and may erode tooth enamel.

Ethylene Glycol

Ethylene glycol is a synthetic, odorless liquid with a sweet taste and water absorption properties. It is commonly used in antifreeze and de-icing solutions for vehicles, hydraulic brake fluids, and certain inks. Although lethal in large ingested quantities, leading to central nervous system depression, cardiopulmonary effects, and renal damage, exposure to low levels can cause minor throat and upper respiratory tract irritation. Chronic exposure in animals has demonstrated kidney toxicity and liver effects. Despite its potential toxicity, ethylene glycol poisoning is unlikely through skin contact and inhalation at room temperature due to its low volatility, though caution should be taken if the liquid is heated or sprayed.

Methylene Dichloride

Methylene dichloride, also known as dichloromethane, is a colorless liquid with a sweet odor that is predominantly used as an industrial solvent, in paint strippers, aerosol and pesticide products, and in the manufacture of photographic film. It does not occur naturally in the environment. Short-term inhalation can cause nervous system effects such as decreased visual, auditory, and motor functions, which are reversible once exposure stops. Long-term exposure can potentially target the central nervous system. Studies are inconclusive about its relation with cancer, but have shown liver injury, increase in liver and lung cancer, and benign mammary gland tumors in animals. Some absorbed methylene chloride is metabolized to carbon monoxide. High exposure can cause trivial hepatotoxicity.

VOCs (Volatile Organic Compounds)

Volatile organic compounds (VOCs) are released by many cleaning products, as revealed by a study in Chemosphere which analyzed 30 such items. Of the 530 distinct VOCs identified, 193 were considered hazardous, linked to health issues like respiratory system damage and cancer. Indoor air contamination from VOCs is significantly higher than outdoor, with up to 10 times more pollutants. However, products labeled as green, particularly those without fragrances, exhibited fewer hazardous VOC emissions. Exposure to VOCs has critical health implications, especially for cleaning industry workers and children, and these compounds also contribute to outdoor air pollution.

Hydrochloric Acid

Hydrochloric acid is used in multiple industries like chlorides, fertilizers, dyes, electroplating, and others. It has dangerous health effects like irritation and inflammation of eyes, nose and respiratory tract, and pulmonary edema after short-term inhalation; corrosion to mucous membranes, esophagus, and stomach and severe burns after oral exposure; dermatitis, photosensitization, gastritis and chronic bronchitis after long-term occupational exposure. While the EPA hasn't classified hydrochloric acid for carcinogenicity, many chemicals can spill to release HCl in water.

Phosphoric Acid

Phosphoric acid, in liquid or solid form, can cause second-degree burns upon contact within minutes. It's usually shipped as a solid or an 85% solution and is corrosive to skin when the concentration is over 70%. This acid is also an irritant to the eyes, skin, and upper respiratory tract, however, the risk of pulmonary edema is minimal.

Potassium Hydroxide

Potassium hydroxide 30-70% is a liquid that is highly corrosive to skin, causing second or third-degree burns even after brief contact. It is a hazardous substance that can also induce pulmonary edema, a condition characterized by excessive fluid in the lungs. The effects and properties of this chemical can be compared to those of Sodium hydroxide.

Triethanolamine

Triethanolamine appears to cause occupational asthma and allergic contact dermatitis in machinists and photographers, as well as liver and kidney damage in animals with high-dose feeding. It's noted to be an irritant to the skin, eyes, and respiratory tract, with potential to cause skin sensitization, though the rate of skin sensitization in humans is low. Triethanolamine has low acute toxicity, with median oral LD50 values of 4,190-11,260 mg/kg in rats and 5,300-8,000 mg/kg in guinea pigs, and a median dermal LD50 greater than 2,000 mg/kg in rabbits. Triethanolamine is not carcinogenic, developmental toxicant, or toxic to the reproductive system. However, chronic exposure may lead to liver and kidney damage.

Monoethanolamine

2-Aminoethanol is a colorless, viscous liquid that, despite not being registered for pesticide use in the U.S, holds vast potential in a variety of applications. It can be used in cutting fluids, production of soaps, surfactants, salts, corrosion control inhibitors, pharmaceuticals, and even in protective topical solutions against chemical warfare agents. Used as a pharmaceutical adjuvant, 2-Aminoethanol is effective as a solvent for fats and oils and in creating emulsion formulas like lotions and creams. However, it poses health risks, as a 5.9% concentration can irritate human skin and inhalation may cause allergic reactions, liver damage, and liver symptoms.

Ethanolamine

Ethanolamine is a liquid that can cause first-degree burns on short exposure. It is known to be a skin irritant and can cause allergic contact dermatitis. Occupational exposure, notably among hairdressers, has been linked to asthma. Inhalation of ethanolamine in high concentrations can lead to Central Nervous System (CNS) depression and can be toxic to the liver, as shown in subchronic inhalation studies in animals. It is also a skin, eye, and respiratory tract irritant, with the potential to sensitize the skin.

Diethanolamine

Diethanolamine is a chemical found in various consumer products like shampoos, cosmetics, and pharmaceuticals. Acute exposure in humans can result in irritation of the nose, throat, and skin. However, no detailed data is available on its chronic, reproductive, developmental or carcinogenic effects on humans. Studies on animals reveal that acute oral exposure can influence the liver, blood, kidney, and central nervous system, while dermal exposure has been connected with an increased incidence of liver and kidney tumors in mice. Production of first-degree burns, skin irritation, occupational asthma, kidney, and liver injury risk, and potential skin sensitization are some other adverse effects associated with diethanolamine.

Benzene

Benzene is a colorless, sweet-smelling, highly flammable liquid that evaporates quickly into the air and slightly dissolves in water. It's a byproduct of both natural processes and human activities, used extensively in the U.S production of other chemicals for plastics, resins, nylon, rubbers, lubricants, dyes, detergents, drugs, and pesticides. Present in crude oil, gasoline, and cigarette smoke, benzene is also released into the air from burning coal, oil, gasoline stations, and vehicle exhaust. Short-term exposure may cause drowsiness, dizziness, and irritation, while long-term exposure leads to blood disorders, reproductive effects, and even leukemia. Benzene has been classified by EPA as a known human carcinogen, and regulations apply to various industry sectors with potentially high exposure risks.

Sources: 
Morpholine

Exposure to high concentrations of morpholine can cause prominent liver damage in animals. Additionally, occupational exposure to this substance can result in skin, eye, and respiratory irritation, but no long-term health effects have been reported. Morpholine is also regarded as corrosive to skin and can induce pulmonary edema.

Sodium Metasilicate

Sodium metasilicate is a type of compound that includes varying amounts of sodium oxide (Na2-O) and silica (Si2-O), and its aqueous solutions are heavily alkaline and corrosive, typically containing weight ratios of silica to sodium oxide between 1.6 to 3.8. It is a strong irritant for skin and eyes and can be toxic if ingested in high doses. In its aerosol form, it can irritate the skin, eyes, and respiratory tract. The compound, tested at specific molar ratios, has shown corrosive effects on rabbit skin but hasn't shown any sensitizing effects in a local lymph node assay study on mice. Both hydrous and anhydrous forms, including Sodium metasilicate pentahydrate, Sodium metasilicate nonahydrate, Sodium silicate, and Potassium silicate, share similar uses and adverse effects, mainly due to their corrosive effects on metal and tissue resulting from their alkalinity.

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Authors

Camille May, Product Curator

Hey, I’m Camille—co-creator of Welpr and your go-to guide for all things clean living. After selling my last company in the health food space, I went non-toxic to heal an autoimmune condition. It did wonders for my health, but navigating which products to buy wasn’t easy. We built Welpr to make that journey feel a bit easier.  When I’m not working on Welpr, you’ll usually find me in the sauna, sipping a raw milk latte while doing a puzzle, or walking with my pit bull Romeo in my hometown of Austin, TX.

Olushola M. Awoyemi, Medical Reviewer

Olushola M. Awoyemi (aka Shola) is a board-certified toxicologist and a research scientist with a PhD in Environmental Toxicology. Shola's long-term ambition is to be recognized as a world-renowned expert in toxicology, risk assessment, and management, with experience spanning across institutions like the US EPA, US FDA, NIEHS, USDA, UNEP, WHO, and possibly within Fortune 100 companies in the Chemical, Healthcare, Pharmaceutical, Consumer goods, or IT sectors.

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