Certifications
Free From
Highlights
1 year warranty
Waterproof
Fitted sheet style
Temperature regulating
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Best Non-Toxic Mattress Protectors
We vetted mattress protectors against the Welpr Standard and here are our top picks.
Cofounder & Product Curator
Medical Reviewer, PhD
Here's what we look for:
- Natural materials like organic cotton and wool
- Minimal, certified-safe synthetics
- No formaldehyde-releasing agents, added flame retardants, PFAS, and low-to-zero VOC
- Trusted third-party certifications whenever available
- Transparent sourcing, materials, and manufacturing practices
Best Non-Toxic Mattress Protectors
On Welpr, terms like "non-toxic," "safer," "cleaner," "healthier," and "vetted" are editorial labels based on our own standard for product assessment. They are not guarantees, certifications, or medical claims. Learn more.
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Certifications
Free From
Highlights
1 year warranty
Waterproof
Fitted sheet style
Temperature regulating
Certifications
Free From
Highlights
Compostable packaging
10 year warranty
Waterproof
Zippered encasement
Temperature regulating
Certifications
Free From
Highlights
Vegan
1 year warranty
Fitted sheet style
Temperature regulating
Certifications
Free From
Highlights
10 year warranty
Waterproof
Fitted sheet style
Temperature regulating
Certifications
Free From
Highlights
Hypoallergenic
10 year warranty
Waterproof
Fitted sheet style
Temperature regulating
Certifications
Free From
Highlights
Vegan
Cruelty-free
Waterproof
Fitted sheet style
Temperature regulating
Certifications
Free From
Highlights
Fitted sheet style
Temperature regulating
Certifications
Free From
Highlights
Made in EU
Hypoallergenic
Money-back guarantee
Fitted sheet style
Temperature regulating
Certifications
Free From
Highlights
Made in EU
Hypoallergenic
Money-back guarantee
Fitted sheet style
Temperature regulating
Certifications
Highlights
Anchor band
Temperature regulating
How to Swap to Non-Toxic mattress protectors:
Here's how to swap to non-toxic mattress protectors:
What to know about mattress protectors
Mattress protectors sit directly under your sheets and stay in contact with your body for hours every night. Because of this extended skin contact and daily use, the materials they're made from matter a lot.
- Many conventional mattress protectors use synthetic waterproof backings that can contain PFAS, phthalates, or release VOCs — chemicals used to make plastics flexible or water-resistant.
- Welpr prioritizes protectors made with natural fibers like organic cotton or wool on the sleeping surface, and only allows plastic or polyester in the waterproof layer if it's free of those chemicals and backed by certifications.
Review what you already use
Check the label or product listing for your current mattress protector. Look at what the sleeping surface is made of and what type of waterproof backing is used.
- If the label says 100% polyester or vinyl on the sleep surface (the side touching your sheets), that's a sign the material sitting closest to you is fully synthetic.
- Look for certifications like OEKO-TEX®, GOTS, or MADE SAFE® — these indicate the product has been tested for common chemicals of concern.
Use your current mattress protector more safely
If you're not ready to replace your mattress protector right away, a few simple steps can help reduce what you're exposed to while you sleep.
- Wash your mattress protector before first use and regularly afterward — this can help reduce residual chemicals from manufacturing.
- Make sure a fitted sheet always goes over the protector so there's a fabric barrier between you and the waterproof layer.
Choose a cleaner replacement
When you're ready to upgrade, look for a mattress protector with a natural fiber sleep surface — like organic cotton or wool — and a waterproof backing that's free of PFAS, phthalates, and VOCs.
- Be cautious of vague claims like "eco-friendly" or "natural" without specific material details or third-party certifications like GOTS, OEKO-TEX®, or MADE SAFE® to back them up.
- Click the button above to shop Welpr Approved mattress protectors.
Camille May
Cofounder & Product Curator
Camille May is the co-creator of Welpr and a guide for clean living. After selling her last company in the health food space, she went non-toxic while working to heal an autoimmune condition....
Olushola M. Awoyemi
Medical Reviewer, PhD
Olushola M. Awoyemi (aka Shola) is a board-certified toxicologist and a research scientist with a PhD in Environmental Toxicology. Shola's long-term ambition is to be recognized as a world-renowned expert in toxicology,...