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Best Non-Toxic Pillowcases

We vetted pillowcases against the Welpr Standard and here are our top picks.

Camille May

Camille May

Cofounder & Product Curator

Olushola M. Awoyemi

Olushola M. Awoyemi

Medical Reviewer, PhD

Here's what we look for:

  • Natural fibers like organic cotton, linen, wool, and hemp
  • Non-toxic dyes and low-impact finishes
  • Trusted third-party certifications like GOTS & OEKO-TEX
  • Brands that are transparent about sourcing, materials, and ethics

Best Non-Toxic Pillowcases

On Welpr, terms like "non-toxic," "safer," "cleaner," "healthier," and "vetted" are editorial labels based on our own standard for product assessment. They are not guarantees, certifications, or medical claims. Learn more.

Smooth Simple Linen Pillowcase (Set of 2)

Smooth Simple Linen Pillowcase (Set of 2)

Rough Linen

Welpr Rating
4.7?
Est. Price$50
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on Rough Linen

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100% Egyptian Cotton Pillowcases (Set of 2)

100% Egyptian Cotton Pillowcases (Set of 2)

California Design Den

Welpr Rating
4.6?
Est. Price$22.99
Buy Now

on Amazon

Organic Cotton Pillowcases (Set of 2)

Organic Cotton Pillowcases (Set of 2)

Delilah Home

Welpr Rating
4.7?
Est. Price$40
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on Delilah Home

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on Amazon

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Crinkled Percale Pillowcase (Set of 2)

Crinkled Percale Pillowcase (Set of 2)

Coyuchi

Welpr Rating
4.7?
Est. Price$38
Buy Now

on Coyuchi

Buy Now

on Amazon

Organic Cotton Sateen Pillowcases (Set of 2)

Organic Cotton Sateen Pillowcases (Set of 2)

Naturepedic

Welpr Rating
4.7?
Est. Price$49
Buy Now

on Naturepedic

Organic Bamboo Pillowcase (Set of 2)

Organic Bamboo Pillowcase (Set of 2)

Sijo

Welpr Rating
4.7?
Est. Price$40
Buy Now

on Sijo

100% Organic Cotton Percale Pillow Case (Set of 2)

100% Organic Cotton Percale Pillow Case (Set of 2)

Sleep & Beyond

Welpr Rating
4.7?
Est. Price$45
Buy Now

on Sleep & Beyond

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on Amazon

LuxeSoft Cotton Pillowcase (Set of 2)

LuxeSoft Cotton Pillowcase (Set of 2)

Sijo

Welpr Rating
4.7?
Est. Price$45
Buy Now

on Sijo

Percale Hemmed Pillowcase (Set of 2)

Percale Hemmed Pillowcase (Set of 2)

Boll & Branch

Welpr Rating
4.7?
Est. Price$59
Buy Now

on Boll & Branch

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on Amazon

Signature Hemmed Pillowcase (Set of 2)

Signature Hemmed Pillowcase (Set of 2)

Boll & Branch

Welpr Rating
4.7?
Est. Price$59
Buy Now

on Boll & Branch

Buy Now

on Amazon

LuxeWeave Linen Pillowcase (Set of 2)

LuxeWeave Linen Pillowcase (Set of 2)

Sijo

Welpr Rating
4.7?
Est. Price$60
Buy Now

on Sijo

Buy Now

on Amazon

Organic Flannel Pillowcases (Set of 2)

Organic Flannel Pillowcases (Set of 2)

Whisper Organics

Welpr Rating
4.6?
Est. Price$27.99
Buy Now

on Amazon

1000 Thread Count Sateen Pillowcases (Set of 2)

1000 Thread Count Sateen Pillowcases (Set of 2)

California Design Den

Welpr Rating
4.6?
Est. Price$27.99
Buy Now

on Amazon

100% Organic Cotton Pillowcases (Set of 2)

100% Organic Cotton Pillowcases (Set of 2)

Whisper Organics

Welpr Rating
4.6?
Est. Price$36.99
Buy Now

on Amazon

Classic Sateen Pillowcase (Set of 2)

Classic Sateen Pillowcase (Set of 2)

Coyuchi

Welpr Rating
4.6?
Est. Price$38
Buy Now

on Coyuchi

Buy Now

on Amazon

AiryWeight Eucalyptus Pillowcase (Set of 2)

AiryWeight Eucalyptus Pillowcase (Set of 2)

Sijo

Welpr Rating
4.6?
Est. Price$45
Buy Now

on Sijo

Buy Now

on Amazon

Cloud Brushed Organic Flannel Pillowcase (Set of 2)

Cloud Brushed Organic Flannel Pillowcase (Set of 2)

Coyuchi

Welpr Rating
4.6?
Est. Price$48
Buy Now

on Coyuchi

Buy Now

on Amazon

Luxury Sateen Pillowcases (Set of 2)

Luxury Sateen Pillowcases (Set of 2)

Brooklinen

Welpr Rating
4.6?
Est. Price$62
Buy Now

on Brooklinen

Buy Now

on Amazon

Organic Relaxed Linen Pillowcase (Set of 2)

Organic Relaxed Linen Pillowcase (Set of 2)

Coyuchi

Welpr Rating
4.6?
Est. Price$128
Buy Now

on Coyuchi

How to Swap to Non-Toxic pillowcases:

Here's how to swap to non-toxic pillowcases:

What to know about pillowcases

Your pillowcase is one of the closest products to your face, mouth, and nose — and you use it every night for hours. That makes the fabric and how it's made especially worth paying attention to. Welpr focuses on the fiber type, dyes, and finishes used in pillowcases to make sure what's touching your skin all night is as clean as possible.

  • Pillowcases made from synthetic fabrics or treated with chemical finishes sit against your face for 6-9 hours at a time, making them a high-priority item to evaluate.
  • Because pillowcases are washed frequently, the dyes and fabric treatments matter — low-quality dyes can break down and transfer to skin over time.

Check what your pillowcases are made of

Look at the care tag or product listing for your current pillowcases to see what fiber they're made from. Welpr prioritizes natural fibers like organic cotton, linen, silk, and hemp over synthetic materials like polyester or microfiber.

  • Check the tag sewn into the seam — it should list the fabric content (e.g., 100% cotton, polyester blend, bamboo viscose).
  • If your pillowcase is labeled "wrinkle-free," "stain-resistant," or "performance fabric," it may have chemical finishes worth looking into further.

Get more out of your current pillowcases

If you're not ready to replace your pillowcases right away, a couple of simple habits can reduce what your skin is exposed to overnight.

  • Wash new pillowcases at least once before sleeping on them to help remove residual dyes, finishes, and manufacturing residues.
  • Wash pillowcases weekly in unscented detergent — frequent washing helps reduce buildup, and skipping synthetic fragrance means fewer additives sitting against your face all night.

Choose cleaner pillowcases

Look for pillowcases made from natural fibers like organic cotton, linen, silk, or hemp. Certifications like GOTS or OEKO-TEX® are a good sign, but Welpr also reviews the materials, brand transparency, and sourcing behind every product.

  • Avoid pillowcases made from 100% polyester or those marketed with wrinkle-free or stain-resistant finishes, and look for products free from azo dyes.
  • Click the button above to shop Welpr Approved pillowcases.
Camille May

Camille May

Cofounder & Product Curator

Camille May is the co-creator of Welpr and a guide for clean living. After selling her last company in the health food space, she went non-toxic while working to heal an autoimmune condition....

Olushola M. Awoyemi

Olushola M. Awoyemi

Medical Reviewer, PhD

Olushola M. Awoyemi (aka Shola) is a board-certified toxicologist and a research scientist with a PhD in Environmental Toxicology. Shola's long-term ambition is to be recognized as a world-renowned expert in toxicology,...