Best Non-Toxic Cleaning Wipes in 2025

Benzyldimethyl(tridecyl)ammonium chloride is a mixture recognized for its bactericidal properties. It is used topically in medicaments, deodorants, mouthwashes, and as surgical antiseptics, and also function as preservatives and emulsifiers in drugs and cosmetics. However, the EPA's assessment based on industry data suggests that this substance presents a significant risk to human health. Moreover, a peer-reviewed study has indicated that some quaternary ammonium compounds can lead to reproductive toxicity in animals.

Formaldehyde is a colorless, flammable gas with a pungent smell that's naturally produced in small quantities in human bodies and is also known as methanal amongst other names. It's used in the production of various items such as fertilizers, paper, plywood, and urea-formaldehyde resins as well as in some foods and household products like antiseptics, medicines, and cosmetics. Exposure to formaldehyde, which can occur through breathing contaminated indoor air, tobacco smoke, or ambient urban air can lead to respiratory symptoms, irritation of the eyes, nose and throat and has been linked to lung and nasopharyngeal cancer as well as leukemia. The EPA considers formaldehyde a probable human carcinogen (Group B1) and inhaling it can cause bronchospasm and pulmonary edema. Commercially, it's sold as formalin in solutions of 37%, 44%, or 50% and long-term exposure can cause first-degree burns, skin sensitization, squamous cell nasal cancer, and chronic pulmonary obstruction.

Methylisothiazolinone can reportedly cause allergic contact dermatitis in workers who interact with products containing it. This substance is recognized as a contact allergen for consumers using cosmetics that include it. It can cause skin burns and sensitization, and inhaling it may lead to corrosive injuries in the upper respiratory tract and lungs. Ingesting this substance is harmful, and inhalation is toxic. This preservative is linked to the category of isothiazolinones.

Butylphenyl methylpropional, also known as lilial, is a chemical compound commonly used in cosmetics and laundry powders. It is found naturally in crow-dipper and tomato plants and is also produced synthetically in large quantities. In May 2019, the EU's Scientific Committee on Consumer Safety (SCCS) deemed its use in cosmetics as unsafe. Following animal studies indicating reproductive toxicity, the EU banned its use in cosmetics by March 2022. Moreover, butylphenyl methylpropional can sometimes serve as an allergen, potentially leading to contact dermatitis in susceptible individuals.

Diethylene glycol ethers is a chemical that has been found to have hematologic, liver, and kidney effects. Exposure to large amounts, about 250 mg/kg/day, can lead to central nervous system depression and other organ damage in rats and may decrease red blood cell counts. It does not show genotoxic, mutagenic, liver, kidney, blood, or reproductive toxicity in animals or humans, but it is classified as an exceptional allergen. The material can be absorbed through the skin and is identified as a mild skin irritant and a severe eye irritant. Notably, its toxicity is lower than that of ethylene glycol ethers.

Diethylene glycol ethers is a chemical that has been found to have hematologic, liver, and kidney effects. Exposure to large amounts, about 250 mg/kg/day, can lead to central nervous system depression and other organ damage in rats and may decrease red blood cell counts. It does not show genotoxic, mutagenic, liver, kidney, blood, or reproductive toxicity in animals or humans, but it is classified as an exceptional allergen. The material can be absorbed through the skin and is identified as a mild skin irritant and a severe eye irritant. Notably, its toxicity is lower than that of ethylene glycol ethers.

Diethylene Glycol Monoethyl Ether, when administered orally or through the skin in doses exceeding 800-1000 mg/kg/day, can cause central nervous system depression and changes to the liver and kidneys in animals. However, it doesn't exhibit significant developmental toxicity at these levels. The chemical is not expected to have adverse effects unless workers are exposed to its heated liquid mists. It is an eye irritant and provokes harm to the central nervous system, liver, kidneys, red blood cells, and reproductive system in animal feeding studies. Despite these potential harms, it is poorly absorbed through the skin.

Galaxolide is recognized as an established contact allergen in humans, according to the Scientific Committee on Consumer Safety's 2011 report on fragrance allergens in cosmetic products. This compound has been identified as a reproductive effector and acts as a moderate skin irritant, as documented in The Registry of Toxic Effects of Chemical Substances (RTECS).

Quaternium-15 is a preservative commonly used in cosmetics which is known to significantly contribute to allergic contact dermatitis in users. This condition has been reported in various professions, including hairdressers, machine maintenance engineers at a chicken processing plant, and photocopy workers. Notably, Quaternium-15, as a formaldehyde releaser, increases dermatitis risk. However, rinse-off products typically pose a lower risk of resulting in allergic contact dermatitis.

Sodium hypochlorite is a clear liquid with a strong chlorine odor, predominantly used as bleaching agents or disinfectants in commercial cleaning solutions and water purification systems. Sodium hypochlorite is often used in a dissolved state. It is corrosive to skin and can cause pulmonary edema from high inhalation exposure. Its ingestion can lead to methemoglobinemia, and a 3% to 5% solution causes burnings of the mouth and throat. The anhydrous form of this compound is highly explosive.

Sodium Lauryl Sulfate is recognised as a skin, eye, and respiratory tract irritant according to ICSC. It may cause allergic reactions and eye irritation as stated by the HSDB. Exposure may even result in eye burns, as per CAMEO. Depending on its form - which may range from a solid (90-98% purity), to a paste (30-41%), or an aqueous solution (28-50%) - it can significantly irritate skin and eyes, with adverse effects escalating with increased concentration. Despite these hazards, it is not a skin sensitizer according to CHEMINFO, while eChemPortal: ERMA and MSDSonline endorse its classification as an irritant.

Sodium metasilicate is a type of compound that includes varying amounts of sodium oxide (Na2-O) and silica (Si2-O), and its aqueous solutions are heavily alkaline and corrosive, typically containing weight ratios of silica to sodium oxide between 1.6 to 3.8. It is a strong irritant for skin and eyes and can be toxic if ingested in high doses. In its aerosol form, it can irritate the skin, eyes, and respiratory tract. The compound, tested at specific molar ratios, has shown corrosive effects on rabbit skin but hasn't shown any sensitizing effects in a local lymph node assay study on mice. Both hydrous and anhydrous forms, including Sodium metasilicate pentahydrate, Sodium metasilicate nonahydrate, Sodium silicate, and Potassium silicate, share similar uses and adverse effects, mainly due to their corrosive effects on metal and tissue resulting from their alkalinity.

Trichloroethylene (TCE) is a colorless, nonflammable liquid primarily used as an industrial solvent, featuring in products like adhesives, paint removers, and correction fluids. It's not natural to the environment but has been found in groundwater and surface waters due to its manufacture and disposal. Exposure to TCE, either short-term or chronic, can impact the central nervous system and cause symptoms such as dizziness, confusion and weakness, while also affecting other organs like the liver and kidneys. It has even been linked to several types of cancer, particularly in the kidneys, liver, cervix and lymphatic system. Although TCE itself poses a low fire hazard, under certain conditions like exposure to flames or other specific metals, it can produce phosgene, a highly toxic gas, or react violently with other strong oxidizers. To handle or transport TCE safely, it should be stored in steel drums in a cool, dry, well-ventilated area.

Isopropyl alcohol has been shown to cause narcosis in animals during acute studies, as cited by ACGIH. However, according to research by Zimmerman, it is not hepatotoxic in either experimental animal studies or in human exposures. It's known to be a skin, eye, and respiratory tract irritant, and if inhaled in high concentrations, it can cause CNS depression, as indicated by the ICSC.

Benzalkonium chloride (BAC) is an organic salt known for its robust antimicrobial properties, effective against various bacteria, viruses, and fungi. It is frequently employed in healthcare settings like hospitals for disinfecting instruments and surfaces. Additionally, BAC is present in many consumer items, including hand sanitizers, wipes, eye solutions, nasal sprays, and personal care products such as soaps and shampoos. Although typically safe when used as instructed, BAC can lead to skin and eye irritation, particularly at elevated concentrations.