Best Non-Toxic Eye Drops in 2025
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What we look for:
- Preservative-free or minimal, well studied options like boric acid
- No unnecessary fillers or harsh additives
- Fragrance-free and dye-free, always
- No parabens, phthalates, sulfates, or benzalkonium chloride
- Full transparency with every ingredient listed
Find Non-Toxic Eye Drops
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User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
TEARS Plus Lubricant Eye Drops Relief for Dry Eyes - Oasis
Product Details
- Suitable for day or night time use.
- Designed to relieve moderate to severe dry eye symptoms.
- Preservative-free to avoid exposure to harmful chemicals.
- Natural blinking helps distribute the drops across the eye surface.
Pros & Cons
Pros
- Provides long-lasting, soothing relief for dry eyes.
- Gentle, irritation-free formula suitable for sensitive eyes.
- Compact vial size reduces waste and is perfect for on-the-go use.
- Recommended by eye care professionals for effectiveness.
- Convenient small packages make them easy to carry.
Cons
- Some users may find the formula too thick or goopy compared to other versions.
- A few individuals noted the vials could contain more for the price.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Active Ingredients: Glycerin (0.22%) Inactive Ingredients: Sodium Chloride, Sodium Hyaluronate, Sodium Phosphate Dibasic, Sodium Phosphate Monobasic, Water
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Optive Gel Drops Lubricant Eye Gel - Refresh
Product Details
- Provides extended relief and protection for dry, irritated eyes by day or night.
- Offers a gel formula that feels like a drop, ensuring lasting comfort.
- Incorporates hydrocell technology for optimal hydration of the eyes.
- Recommended by doctors with extensive experience in eye care.
Pros & Cons
Pros
- Instantly soothes dryness, providing significant comfort.
- Long-lasting relief reduces the need for frequent reapplication.
- Effective for both daily use and specific needs like post-medical procedures.
- Recommended by eye care professionals for dry eye conditions.
Cons
- Some users may experience short-term blurry vision due to the gel's viscosity.
- May not be optimal for use with contact lenses for certain individuals.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Boric Acid, Calcium Chloride Dihydrate, Erythritol, Levocarnitine, Magnesium Chloride Hexahydrate, Potassium Chloride, Purified Water, Purite® (Stabilized Oxychloro Complex), Sodium Borate Decahydrate, Sodium Citrate Dihydrate
Lubricating Eye Drops - Bausch + Lomb
Product Details
- Preservative-free formula mimics natural tears for safe, fast-acting relief from dryness.
- Infused with hyaluronan, an electrolyte, and an antioxidant to enhance moisture retention.
- Gentle enough for everyday use to soothe irritation without preservatives.
- Provides temporary relief from burning and discomfort due to environmental factors.
- Contact lens friendly, ensuring comfort whether indoors or outdoors.
Pros & Cons
Pros
- No preservatives, ideal for frequent use and those with allergies.
- Instantly soothing and effective for dry, irritated eyes.
- Convenient single-use droppers make them perfect for on-the-go.
- Recommended by professionals post-eye surgery for optimal eye health.
- Calming relief without stinging or blurring vision.
Cons
- Some users find the bottle design a bit tricky and less intuitive.
- Relief is temporary and may require frequent reapplication for sustained comfort.
Ingredients
Ingredients: Glycerin (0.75%), L-Arginine (Amino Acid), Calcium Chloride, Citric Acid, Cyanocobalamin (Vitamin B12), L-Leucine (Amino Acid), Magnesium Ascorbyl Phosphate (Vitamin C Derivative), Potassium Chloride, Sodium Borate, Sodium Chloride, Sodium Hyaluronate, Sodium Hydroxide, Taurine, Water
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Lid and Lash Cleanser Spray - Heyedrate
Product Details
- Deeply cleanses eyelids and lashes by removing dirt, oil, and bacteria.
- Gentle hypochlorous acid formula provides soothing relief for dry, itchy eyes.
- Formulation free from alcohol, fragrance, parabens, sulfates, and preservatives.
- Easy application with a pump bottle for quick and effective cleansing.
- Helps maintain eye health with ethical practices by contributing to eye care for those in need.
Pros & Cons
Pros
- Provides effective relief for dry, irritated eyes and helps with conditions like blepharitis and styes.
- Gentle and soothing on sensitive eyes, making it suitable for daily use.
- Fragrance-free with minimal ingredients, appealing to those avoiding harsh chemicals.
- Offers quick relief and long-lasting effects, especially for eye irritation and swelling.
- User-friendly application that doesn't require precise aiming like eye drops.
Cons
- Some users find the spray bottles inconsistent or problematic, requiring improvements.
- May be considered pricey by some users, especially for frequent use or larger sizes.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Hypochlorous Acid, Electrolyzed Water, Sodium Chloride
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Natural Eye Drops for Redness Relief - Sunnie
Product Details
- Provides daily relief for red, puffy eyes without harsh chemicals.
- Soothes irritation and inflammation with homeopathic botanicals like chamomile and Euphrasia.
- Hydrates and protects with hyaluronic acid to reduce tear evaporation.
- Free from vasoconstrictors and preservatives for gentle, ongoing use.
- Safe for contact lens wearers and sensitive eyes.
Pros & Cons
Pros
- Provides quick and effective relief from redness and dryness.
- Made with 100% plant-based ingredients for a natural eye care option.
- Safe and gentle enough for daily use without irritation.
- Designed with sustainability in mind to reduce single-use plastic waste.
- Good value as a small amount goes a long way.
Cons
- Some users may prefer more frequent application for ongoing relief.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Euphrasia, Chamomile, Pasque Flower (Pulsatilla), Hepar Sulphuris Calcareum, Hyaluronic Acid, Purified Water, Propylene Glycol, Sodium Borate, Boric Acid, Pyridoxine Hydrochloride (Vitamin B6, Borate, Boric Acid), Citric Acid
Organic Tears - Eyeganics
Product Details
- Provides instant relief and protection from eye dryness and irritation.
- Made with USDA-certified organic, plant-based ingredients.
- Preservative-free formula in a contamination-resistant bottle.
- Easy-to-use design for precise, controlled drop dispensing.
- Backed by a satisfaction guarantee with free returns.
Pros & Cons
Pros
- Provides soothing, long-lasting relief for dry, sensitive, or allergy-prone eyes.
- Formulated with minimal, organic ingredients ideal for sensitive skin and those allergic to petroleum-based products.
- Effective for chronic conditions like Sjogren’s syndrome and eczema-related dry eye.
- Highly praised as a natural alternative to prescription eye drops with comparable or better results.
- Gentle and non-irritating, suitable for daily use and sensitive eyes.
Ingredients
Ingredients: Glycerin, Sodium Chloride, Water
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Digital Eye Strain Eye Drops - Sunnie
Product Details
- Helps relieve eye strain, dryness, and light sensitivity from screen use.
- Homeopathic formula supports tired, red, and irritated eyes.
- Includes plant-based cellulose to moisten and protect the eye surface.
- Free from preservatives and vasoconstrictors for gentle daily use.
- Safe for contact lens wearers and suitable for ongoing digital exposure.
Pros & Cons
Pros
- Provides instant relief and moisturization for dry and tired eyes.
- Preservative-free formula is gentle and suitable for sensitive eyes.
- Convenient multi-dose packaging makes it easy to use on the go.
- Effective in reducing dryness and discomfort caused by digital eye strain.
- Formulated with 100% plant-based ingredients for a natural approach.
Cons
- Some users may find the need to blink frequently and take breaks necessary when using with screens to maximize effectiveness.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Senega Officinalis, Ruta Graveolens, Conium Maculatum, Hypromellose, Purified Water, Propylene Glycol, Sodium Borate, Boric Acid, Citric Acid
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Natural Eye Drops for Dry Eyes - Sunnie
Product Details
- Provides daily moisture relief for severe dryness and irritation.
- Formulated with natural ingredients and free from vasoconstrictors.
- Homeopathic blend helps soothe dryness, inflammation, and allergic irritation.
- Includes hyaluronic acid to retain moisture and reduce tear evaporation.
- Preservative-free and safe to use with contact lenses.
Pros & Cons
Pros
- Formulated with 100% plant-derived ingredients for a natural dry eye relief option.
- Soothes and moisturizes dry, irritated eyes to provide comfort.
- Preservative-free, making it suitable for sensitive eyes.
- Offers long-lasting relief, especially in formulations designed for extended use.
- Compatible with contact lenses for all-day comfortable wear.
Cons
- Some users may experience tearing after application, which could be a consideration for sensitive eyes.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Euphrasia, Belladonna, Hyaluronic Acid, Purified Water, Propylene Glycol, Sodium Borate, Boric Acid, Citric Acid
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Preservative Free Eye Drops - Rain
Product Details
- Provides effective, long-lasting relief for moderate to severe dry eyes, keeping them comfortable and refreshed.
- Compatible with contact lenses, offering soothing hydration without affecting your lenses.
- Free from preservatives and harsh chemicals, ideal for sensitive eyes to reduce irritation and provide gentle relief.
- Mimics the natural hydration of tears, offering immediate comfort and alleviating dryness and irritation.
- Features CMS Eye Moisture technology for extended hydration, maintaining moisture and protecting against dryness.
Pros & Cons
Pros
- Gentle and soothing, ideal for dry eyes and sensitive users.
- Preservative-free formula aligns with health-conscious preferences.
- Portable and convenient for active lifestyles, perfect for on-the-go use.
- Users report noticeable improvement in eye comfort and vision clarity.
- Effective for individuals with severe dry eyes, offering immediate relief.
Cons
- Some users find the dispenser difficult to use, especially the individual vials.
- Environmental concerns regarding plastic waste from packaging.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Calcium Chloride, Hydrochloric Acid, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Chloride, Sodium Hydroxide, Sodium Lactate
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Manuka Dry Eye Drops - Optimel
Product Details
- Made with natural, pharmaceutical-grade manuka honey for eye comfort.
- Helps hydrate and alleviate symptoms of dry eye and inflammation.
- Fast-acting relief for sore, irritated eyes and eyelids.
- Honey traceable to sustainable sources in Australia and New Zealand.
Pros & Cons
Pros
- Provides noticeable relief for dry eyes with prolonged use.
- Contains natural Manuka honey, known for its antibacterial and anti-inflammatory properties.
- Some users find it refreshes and hydrates eyes effectively, promoting natural tear production.
- Helps improve eyesight clarity for individuals with chronic dry eye issues.
Cons
- Some users experience a stinging sensation upon application, which might concern those with low pain tolerance.
- A few users noted the product's acidity, potentially impacting those sensitive to pH variations.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Active: Glycerin 0.2%, Inactive: Honey (Leptospermum Spp.), Sodium Benzoate, Sodium Chloride, Water
Common Harmful Chemicals in Eye Drops
Chemical Name
Why it’s harmful
Benzalkonium chloride, when used as a spermaticide, can cause vaginal irritation. A fatal dose by ingestion is 1-3 grams, with symptoms including vomiting, convulsions, and coma. It is corrosive to eyes, a skin irritant, and can cause allergic contact dermatitis, methemoglobinemia and hemolysis. It has a potential to kill within 1-3 hours if concentrated solutions are ingested. Despite the threat it poses, there are no data on its carcinogenicity or teratogenicity and it doesn't interfere with embryo development in rats.
Cetrimonium Bromide is a versatile substance utilized in various products, including topical anti-bacterial and anti-fungal preparations, cosmetics, hair care, throat lozenges, antiseptic gels, and vaccine production. It serves as a surfactant and emulsifier and typically requires skin contact to cause a rash. Its applications range from skincare and haircare products to throat lozenges and vaccine production.
Polyquaternium, modified polymers through quaternization are known for skin toxicity and allergenicity. Prolonged exposure, especially for hairdressers and janitors, may pose risks. It's found in various products, including hair conditioners, creams, and household cleaning items. Concerns include skin irritation, formaldehyde release, and contact dermatitis. Regulations in the EU limit Quaternium-15 to 0.2% in cosmetics, while the US lacks specific regulations.
Chlorhexidine, in its various forms, is primarily used in disinfectants, cosmetics, and pharmaceutical products in the U.S. Chlorhexidine acetate is acutely toxic when applied to the eye and can cause skin reactions, with some instances resulting in severe reactions such as anaphylactic shock. It can also cause discoloration of teeth and damage to the knees. Occupational exposure can lead to asthma in health care workers. Animal studies have shown ocular irritation in rabbits, and while there are mixed results in bacterial mutagenic studies, no carcinogenic effects were noted in long-term studies.
Sodium borate, a toxic white powder, is used in various products ranging from cleaning agents and personal care items to children's toys for pH adjustment. Commonly known as borax, it's found in cleaners, detergents, air fresheners, diaper creams, and some toys like playdough. Although often considered a "green" component, sodium borate can lead to organ system toxicity, fertility issues, harm to an unborn child, endocrine disruption, skin allergies, eye and respiratory irritation, and damage to the male reproductive system. Canada has imposed restrictions on its use in cosmetics.
Assessment of consumer exposure to boron in cleaning products: a case study of Canada, Watch Out For Borax, Borax: Not the green alternative it's cracked up to be, Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout ,
Ethylene glycol is a synthetic, odorless liquid with a sweet taste and water absorption properties. It is commonly used in antifreeze and de-icing solutions for vehicles, hydraulic brake fluids, and certain inks. Although lethal in large ingested quantities, leading to central nervous system depression, cardiopulmonary effects, and renal damage, exposure to low levels can cause minor throat and upper respiratory tract irritation. Chronic exposure in animals has demonstrated kidney toxicity and liver effects. Despite its potential toxicity, ethylene glycol poisoning is unlikely through skin contact and inhalation at room temperature due to its low volatility, though caution should be taken if the liquid is heated or sprayed.
Benzalkonium chloride (BAC) is an organic salt known for its robust antimicrobial properties, effective against various bacteria, viruses, and fungi. It is frequently employed in healthcare settings like hospitals for disinfecting instruments and surfaces. Additionally, BAC is present in many consumer items, including hand sanitizers, wipes, eye solutions, nasal sprays, and personal care products such as soaps and shampoos. Although typically safe when used as instructed, BAC can lead to skin and eye irritation, particularly at elevated concentrations.
Ecological Risk Analysis for Benzalkonium Chloride, Benzethonium Chloride, and Chloroxylenol in US Disinfecting and Sanitizing Products, Evaluation of pulmonary toxicity of benzalkonium chloride and triethylene glycol mixtures using in vitro and in vivo systems, Quaternary Ammonium Compounds in Cleaning Products, Impact of benzalkonium chloride, benzethonium chloride and chloroxylenol on bacterial antimicrobial resistance, Benzalkonium Chloride, SpecialChem: benzalkonium-chloride, Impact of benzalkonium chloride, benzethonium chloride and chloroxylenol on bacterial antimicrobial resistance
Quaternium-15 is a preservative commonly used in cosmetics which is known to significantly contribute to allergic contact dermatitis in users. This condition has been reported in various professions, including hairdressers, machine maintenance engineers at a chicken processing plant, and photocopy workers. Notably, Quaternium-15, as a formaldehyde releaser, increases dermatitis risk. However, rinse-off products typically pose a lower risk of resulting in allergic contact dermatitis.