Best Non-Toxic Face Moisturizer in 2025
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What we look for:
- Simple formulas with fully natural or safe synthetic ingredients
- No parabens, PEGs, phthalates, harsh sulfates, BHA/BHT, artificial dyes, formaldehyde or formaldehyde-releasing ingredients, or undisclosed synthetic fragrance (unless certified safe)
- Minimal, non-irritating preservatives
- EU-compliant brands with third-party certifications when available
- Full transparency around sourcing, ingredients, and manufacturing practices
Find Non-Toxic Face Moisturizer
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User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Facial Moisturizer with Ceramides and Sea Buckthorn - DIME Beauty
Product Details
- Provides deep hydration and relief from irritation with nourishing ingredients.
- Locks in moisture overnight, reducing the appearance of fine lines and pores.
- Contains gentle ingredients that work with your skin's natural renewal process.
- Suitable for all skin types, including dry, sensitive, and oily skin.
- Features clean, vegan, and cruelty-free formulas with sustainable packaging.
- Contains ingredients with a safe Environmental-Working-Group rating for daily use.
Pros & Cons
Pros
- Hydrating and weightless, perfect for dry and combination skin.
- Clear improvement in skin softness and hydration, especially in winter.
- Non-toxic ingredients with a reassuring EWG score of 0.
- Light texture that doesn't cause breakouts, ideal for sensitive or young skin.
Cons
- A few users have noted a smoky smell which may not be appealing to everyone.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Water, Glycerin, Cetearyl Alcohol, Ethylhexyl Olivate, Isononyl Isononanoate, Glyceryl Stearate, Pentylene Glycol, 1,2 Hexanediol, Behenyl Alcohol, Simmondsia Chinensis (Jojoba) Seed Oil, Squalane, Sodium Stearoyl Lactylate, Hydroxyacetophenone, Caprylic/Capric Triglyceride, Butyrospermum Parkii (Shea) Butter, Carbomer, Xanthan Gum, Camellia Oleifera Seed Oil, Olea Europaea (Olive) Fruit Unsaponifiables, Stearyl Glycyrrhetinate, Tetrasodium Glutamate Diacetate, Linoleic Acid, Phospholipids, Phytosterols, Ceramide NP, Hydroxypropyl Cyclodextrin, Sodium Hyaluronate, Glycolipids, Soybean Phytosterols, Aloe Barbadensis Leaf Juice, Hippophae Rhamnoides Fruit Oil, Palmitoyl Tripeptide-38
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Golden Hour Recovery Cream - Ursa Major
Product Details
- Provides deep hydration and quick soothing absorption for all skin types.
- Works as a recovery and anti-aging cream to improve fine lines and dryness.
- Features a plant-based formula with ingredients like sea buckthorn and calendula.
- Made without chemicals, including parabens, sulfates, and synthetic fragrances.
- Suitable for use as a night cream and protective winter face cream.
Pros & Cons
Pros
- Lightweight and non-greasy, perfect for use under makeup.
- Rich, deeply hydrating formula that absorbs quickly.
- Natural ingredients without harsh chemicals or artificial fragrances.
- Leaves skin feeling soft, smooth, and revitalized.
- Well-suited for sensitive skin, free from irritation for many users.
Cons
- Some users with highly sensitive skin may experience irritation.
- May not provide significant results for everyone.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Aloe Barbadensis (Aloe Vera) Leaf Juice*, Helianthus Annuus (Sunflower) Seed Oil, Glyceryl Stearate Citrate, Cetearyl Alcohol, Leuconostoc/Radish Root Ferment Filtrate, Glycerin*, Limnanthes Alba (Meadowfoam) Seed Oil, Galactoarabinan, Cetyl Palmitate, Undecylenic Glycerides, Octyldodecanol, Ribes Nigrum (Black Currant) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Tocopherol, Rosmarinus Officinalis (Rosemary) Leaf Extract, Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract*, Santalum Spicatum (Sandalwood) Wood Oil, Rosa Damascena (Rose) Flower Oil*, Citrus Aurantium Amara (Neroli) Flower Oil*, Cymbopogon Martinii (Palmarosa) Leaf Oil, Calendula Officinalis (Calendula) Flower Extract*, Sodium Phytate, Sodium Anisate, Glyceryl Caprylate, Sclerotium Gum, Xanthan Gum, Alcohol, Citric Acid (* Denotes Organic)
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
The Daily Calm Lightweight Moisturizer - Honest Beauty
Product Details
- Designed for sensitive skin, helping to visibly reduce redness and strengthen the skin barrier.
- Hydrates and calms with hyaluronic acid and allantoin for a deeply moisturized feeling.
- Free from parabens, phthalates, PEGs, dyes, and fragrances for peace of mind.
- Gentle on sensitive skin, hypoallergenic, and dermatologist approved.
- Vegan and cruelty-free formula, accepted by the National Eczema Association.
Pros & Cons
Pros
- Lightweight and non-greasy, perfect for everyday use.
- Contains clean, non-toxic ingredients that are gentle on sensitive skin.
- Fragrance-free option available, minimizing the risk of irritation.
- Hydrates well and helps improve skin texture and redness.
- Easy and effective application with user-friendly packaging.
Cons
- Some users notice a slight smell which might not appeal to everyone.
- A few users find it a bit heavy for oily skin, preferring it for nighttime or seasonal use.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Water (Aqua/Eau), Caprylic/Capric Triglyceride, Neopentyl Glycol Diethylhexanoate, Polyglyceryl-2 Stearate, Cetearyl Alcohol, Propanediol, Cetyl Alcohol, Glycerin, Phytosterols, Phospholipids, Hydrolyzed Sodium Hyaluronate, Trisodium Ethylenediamine Disuccinate, Sclerotium Gum, Hydroxyacetophenone, Allantoin, Linoleic Acid, Jojoba Esters, Tocopherol, Cetearyl Phosphate, Sodium Hydroxide, 1,2-Hexanediol, Caprylyl Glycol, Citric Acid
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
La Crème All-In-One Daily Moisturizer - Dore
Product Details
- Hydrates, repairs, and illuminates for a smooth, glowing complexion.
- Formulated with marine algae, hyaluronic acid, and white lily extract for deep hydration and nourishment.
- Fragrance-free, cruelty-free, and suitable for all skin types, including sensitive and oily skin.
- Provides 24/7 hydration and can be used as a morning or night moisturizer.
- Made in France with clean, non-toxic ingredients, suitable for dry, eczema-prone, and sensitive skin.
Pros & Cons
Pros
- Lightweight and absorbs quickly without leaving a greasy residue.
- Fragrance-free, ideal for sensitive skin and those avoiding scents.
- Moisturizes effectively, leaving skin soft and hydrated.
- Unique pump dispenser maintains product hygiene and is easy to use.
Cons
- Some users note the moisturizer is basic and doesn't offer significant skincare benefits.
- The bottle design may lead to product being left unused when it's near empty.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Aqua (Water/Eau), Glycerin, Dicaprylyl Ether, Coco-Caprylate/Caprate, Butyrospermum Parkii (Shea) Butter, Propanediol Dicaprylate, Tapioca Starch, Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters, Glyceryl Stearate, Glyceryl Stearate Citrate, Behenyl Alcohol, Lauryl Laurate, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Sodium Stearoyl Lactylate, Sodium Levulinate, Cera Alba (Beeswax/Cire D'abeille), Helianthus Annuus (Sunflower) Seed Oil, Xanthan Gum, Sodium Benzoate, Sodium Anisate, Salicylic Acid, Sodium Hyaluronate, Aloe Barbadensis Leaf Extract, Alaria Esculenta Extract, Lilium Candidum Flower Extract, Pelvetia Canaliculata Extract, Sodium Citrate, Tocopherol, Dehydroacteic Acid, Benzyl Alcohol
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Lightweight Moisturizer - Alder New York
Product Details
- Hydrates skin without clogging pores, thanks to hyaluronic acid and lightweight sunflower oil.
- Improves skin firmness and creates a smoother complexion with Tripeptide-5.
- Vitamin C and E correct the appearance of hyperpigmentation and dark spots.
- Matte finish, keeping your skin looking fresh without shine.
- Unscented and fragrance-free, perfect for sensitive skin.
- Clean and vegan formula, suitable for all skin types and genders.
Pros & Cons
Pros
- Non-sticky formula that absorbs easily.
- Leaves skin feeling soft and smooth.
- EWG verified for health-conscious users.
- Effective and gentle cleanser option available.
- Consistently positive brand experience.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Water/ Eau, Helianthus Annuus (Sunflower) Oil, Glyceryl Stearate, 3-Glyceryl Ascorbate (Vitamin C), Glycerin, Cetyl Alcohol, Cetearyl Alcohol, Sodium Stearoyl Lactylate, DL-Panthenol (Vitamin B5), Tocopheryl Acetate (Vitamin E), Palmitoyl Tripeptide-5, Sodium Hyaluronate, Caprylyl Glycol, Ethylhexylglycerin
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Hydrating Face Cream - Cocokind
Product Details
- Nourishes skin with a blend of antioxidants, essential fatty acids, and vitamins for all-day hydration.
- Helps improve skin tone by minimizing the appearance of large pores and smoothing fine lines.
- Leaves a smooth satin finish while being sensitive skin-friendly, vegan, cruelty-free, and essential oil-free.
- Suitable for daily use, morning or evening, to support the skin barrier.
- Delivers hydration and skin barrier support for glowy, happy skin without compromising on formulation.
Pros & Cons
Pros
- Clean, non-toxic ingredients for peace of mind.
- Lightweight formula that absorbs well without a greasy feel.
- Effectively hydrates and improves skin texture.
Cons
- Some users with sensitive skin may experience breakouts or irritation.
- The natural scent, reminiscent of celery, may not be ideal for everyone.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Water/Aqua, Cucumis Sativus (Cucumber) Fruit Water, Squalane, Caprylic/Capric Triglyceride, Helianthus Annuus (Sunflower) Seed Oil, Cetyl Alcohol, Glyceryl Stearate, Butyrospermum Parkii (Shea) Butter, Glyceryl Caprylate, Xanthan Gum, Stearic Acid, Ethylhexylglycerin, Arginine, Lecithin, Pullulan, Glycerin, Caprylhydroxamic Acid, Sorbitan Trioleate, Sodium Phytate, Sclerotium Gum, Tanacetum Vulgare Extract, Panax Ginseng Root Extract, Camellia Japonica Seed Oil, Mentha Piperita (Peppermint) Extract, Cucumis Sativus (Cucumber) Fruit Extract, Apium Graveolens (Celery) Seed Extract, Linum Usitatissimum (Linseed) Seed Extract
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Face Cream Bar - Attitude
Product Details
- Formulated with naturally sourced ingredients like watercress extract, phytoglycogen, and peptides to nourish and rejuvenate skin.
- Helps reduce signs of aging by smoothing fine lines and wrinkles.
- Eco-friendly with biodegradable, plastic-free packaging.
- Vegan and cruelty-free product choice for conscientious consumers.
- EWG verified for containing no ingredients of concern.
Pros & Cons
Pros
- Packaging is eco-friendly and plastic-free, appealing to environmentally conscious users.
- Contains clean ingredients, making it a safer choice for sensitive skin.
- Easy to apply and great for travel due to solid stick form.
- Recyclable packaging adds to sustainability efforts.
Cons
- Some users find the packaging a bit flimsy and not very secure, which might be inconvenient during travel.
- Could be too heavy or waxy for users with oily or combination skin, requiring adjustments in use.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Helianthus Annuus (Sunflower) Seed Wax, Butyrospermum Parkii (Shea) Butter, Jojoba Esters, Argania Spinosa (Argan) Kernel Oil, Dicaprylyl Ether, Glycerin, Olus Oil, Undecane, Caprylic/Capric Triglycerides, Tridecane, Behenyl Behenate, Aqua/Water/Eau, Zea Mays (Corn) Starch, Polyhydroxystearic Acid, Sucrose Laurate, Sucrose Stearate, Acacia Decurrens Flower Wax, Polyglycerin-3, Euphorbia Cerifera (Candelilla) Wax, Glycogen, Hydrolyzed Soy Protein, Nasturtium Officinale (Watercress) Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Rice Amino Acids, Caprylhydroxamic Acid, Glyceryl Caprylate, Hydrolyzed Adansonia Digitata (Baobab) Seed Extract, Proline
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Frankincense Face Balm - Toups & Co
Product Details
- Combines tallow and frankincense to deeply hydrate and soothe the skin.
- Reduces redness and irritation while promoting a more even skin tone.
- Supports skin regeneration for a smoother, more youthful complexion.
- Rich in fatty acids that mimic the skin’s natural barrier without clogging pores.
- Rooted in ancestral skincare traditions, refined for modern daily use.
Pros & Cons
Pros
- Deeply hydrates and smooths skin, leaving a soft, healthy glow.
- Can help reduce redness and improve the appearance of rosacea and blackheads.
- Lightens makeup needs by improving overall skin texture and tone.
- Velvety, nourishing feel with a little going a long way.
- Non-toxic formula aligns with holistic skincare and nutrition values.
Cons
- Results may vary depending on individual skin concerns and consistency of use.
Ingredients
Ingredients: 100% Grass-Fed Tallow, *Organic Virgin Olive Oil, *Organic Frankincense Essential Oil
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Active Algae Lightweight Moisturizer - Kora Organics
Product Details
- Provides long-lasting hydration for a healthy-looking complexion.
- Achieve deep hydration without excess shine for a smooth, matte finish.
- Formulated with green tea, alpine rose, and green algae for enhanced skin clarity.
- Certified organic, cruelty-free, and vegan with no artificial colors or fragrances.
- Suitable for sensitive skin, ensure to patch test before use.
Pros & Cons
Pros
- Lightweight and deeply moisturizing, leaving skin hydrated without a greasy feel.
- Great for sensitive and acne-prone skin, soothing and smoothing texture.
- Contains non-toxic ingredients and is EWG certified, reassuring for health-conscious users.
- Lovely packaging with environmentally-friendly refill options.
Cons
- Some users noted an off-putting smell, which might affect those sensitive to scents.
- Occasional issues with packaging, such as unsealed containers, may concern some buyers.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Aloe Barbadensis Leaf Juice*, Glycerin, Helianthus Annuus (Sunflower) Seed Oil*, Isoamyl Laurate, Water/Aqua/Eau, Triheptanoin, Glyceryl Stearate Citrate, Chlamydomonas Reinhardtii Extract, Coco-Caprylate/Caprate, Polyglyceryl-3 Stearate, Lactobacillus Ferment, Hydrogenated Lecithin, Xylityl Sesquicaprylate, Lysolecithin, Sclerotium Gum, Dilinoleic Acid/Butanediol Copolymer, Chlorophyllin-Copper Complex, Lactobacillus, Xanthan Gum, Pullulan, Potassium Sorbate, Citric Acid, Anhydroxylitol, Lecithin, Tocopherol, Morinda Citrifolia Fruit Extract*, Cocos Nucifera Fruit Extract, Pelargonium Graveolens (Geranium) Flower Oil, Camellia Sinensis Leaf Extract*, Rhododendron Ferrugineum Extract, Silica, Castor Oil/IPDI Copolymer, Ocimum Basilicum (Basil) Oil, Rosa Centifolia (Rose Moroccan) Flower Oil, Alcohol, Citronellol**, Geraniol**
Clarifying Cream - Primally Pure
Product Details
- Calms breakouts and irritation with healing botanicals
- Lightweight, non-comedogenic formula that won’t clog pores
- Restores and supports the skin’s natural moisture barrier
- Evens skin tone and boosts radiance
- Protects from environmental stressors for a healthy glow
Pros & Cons
Pros
- Combines treatment and moisture in one easy step, simplifying skincare routines.
- Effectively helps clear acne without drying out the skin.
- Restores skin barrier and reduces active breakouts.
- Highly moisturizing with a little product going a long way.
- Gentle enough for various ages and skin types, including sensitive and oil-rich skin.
Cons
- Some users wish the product lasted longer due to frequent use.
Ingredients
Ingredients: Organic Tallow from Grass-Fed Cows, Emu Oil, Organic Jojoba Oil, Essential Oils of Organic Bergamot (Bergaptene-Free), Organic Neroli, Wildcrafted Manuka and Organic Tea Tree, Organic Rosemary Extract, Non-GMO Vitamin E
Fresh Face Tallow Cream - Pretty Farm Girl
Product Details
- Deeply hydrates and soothes skin overnight with organic rose water and aloe.
- Ideal for sensitive, dry, or combination skin types for a soft and supple complexion.
- Contains potent antioxidants to protect against environmental stressors and support natural skin regeneration.
- Non-greasy and fast-absorbing, providing lasting moisture without residue.
- Cruelty-free and organic, aligning with sustainable skincare values.
Pros & Cons
Pros
- Excellent moisturizer without a greasy feel.
- Helps reduce fine lines and improves skin brightness and tightness.
- Delightful texture that transforms from mousse to oil.
- A small amount goes a long way, enhancing value.
- Beneficial for skin prone to redness and irritation.
Cons
- Some users might find the scent off-putting.
- Not ideal for those who require specific acne treatments.
Ingredients
Ingredients: Organic Grass-Fed Tallow, Rose Essential Oil, Frankincense Essential Oil, Nilotica Shea Butter, Lavender Essential Oil, Emu and Tamanu Oil
Moisturize Me Ultra-Rich Repair Facial Cream - Fre
Product Details
- Promotes intense hydration for dry and sensitive skin.
- Helps reduce the appearance of fine lines and wrinkles.
- Formulated with argania active complex and shea butter for nourishing care.
- Suitable for daily use as a part of a skincare routine.
- Free from harsh chemicals, ideal for health-conscious users avoiding toxic products.
Pros & Cons
Pros
- Rich and thick cream ideal for nighttime use, deeply hydrates and plumps skin.
- Non-plastic, eco-friendly glass jar minimizes potential chemical exposure.
- Contains beneficial ingredients like ceramides and rosehip oil for optimal skin health.
- Fresh, inviting scent that is not overly feminine.
Cons
- Some may find the heavy scent unsuitable, especially those sensitive to fragrances.
Ingredients
Ingredients: (Ein Gedi Spring) Water, Potassium Olivoyl Hydrolyzed Oat Protein, Butyrospermum Parkii (Shea) Butter, Rose Hip Seed Oil, Phospholipids, Urea, Glycosphingolipids, Argania Spinosa Leaf Extract, Argania Spinosa Kernel Oil, Cetearyl Alcohol, Theobroma Cacao Seed Butter, Glycerin, Glyceryl Oleate, Glyceryl Stearate, Carnauba (Copernicia Cerifera) Wax, Acetyl Tetrapeptide-2, Cetyl Alcohol, Vitis Vinifera Seed Oil, Silica, Alpha-Glucan Oligosaccharide, Hyaluronic Acid, Saccharide Isomerate, Tocopherol, Isomalt, Argania Spinosa Callus Culture Extract, Levulinic acid, p-Anisic acid, Carbomer, Xanthan Gum, Lecithin, Ylang-Ylang (Cananga Odorata) Flower Oil
Common Harmful Chemicals in Face Moisturizer
Chemical Name
Why it’s harmful
Benzalkonium chloride, when used as a spermaticide, can cause vaginal irritation. A fatal dose by ingestion is 1-3 grams, with symptoms including vomiting, convulsions, and coma. It is corrosive to eyes, a skin irritant, and can cause allergic contact dermatitis, methemoglobinemia and hemolysis. It has a potential to kill within 1-3 hours if concentrated solutions are ingested. Despite the threat it poses, there are no data on its carcinogenicity or teratogenicity and it doesn't interfere with embryo development in rats.
Benzophenone (BZP) is a photoinitiator, fragrance enhancer, and ultraviolet stabilizer, used in a variety of industrial applications. Despite not being registered as a pesticide in the U.S., it's involved in the production of insecticides and agricultural chemicals. Its toxic effects on humans are scarcely documented, but it presents little hormonal activity on cell lines. Animal studies show it possesses no estrogenic activity, but it can transform into derivatives with such activity under UV irradiation. It did not show reproductive toxicity or carcinogenicity in rats and mice, respectively, even at high doses. It can be bioactivated through specific enzymes. For aquatic life, fathead minnow larvae were more sensitive to BZP, ranking it in the middle of the toxicity order of six benzene derivatives.
Benzophenone & Related Compounds, Chemical Profile: Benzophenone, Toxicological evaluation of benzophenone, Benzophenone – information sheet, Proposition 65 Warnings: Benzophenone, OEHHA: Benzophenone, FDA Removes 7 Synthetic Flavoring Substances from Food Additives List, Benzophenone-3, a chemical UV-filter in cosmetics: is it really safe for children and pregnant women? ,
Cetrimonium Bromide is a versatile substance utilized in various products, including topical anti-bacterial and anti-fungal preparations, cosmetics, hair care, throat lozenges, antiseptic gels, and vaccine production. It serves as a surfactant and emulsifier and typically requires skin contact to cause a rash. Its applications range from skincare and haircare products to throat lozenges and vaccine production.
Homosalate is a commonly used chemical in sunscreens and SPF-containing skincare products, primarily known for its UV-absorbing properties. However, it is a potential endocrine disruptor, particularly affecting the estrogen, androgen, and progesterone hormone systems. Studies in breast cancer cells indicate increased cell growth and multiplication following homosalate exposure. Moreover, homosalate's presence in human breast milk and its estrogenic activity in placental tissues raise concerns about its impact during vulnerable developmental stages. Additionally, homosalate has been shown to enhance the absorption of pesticides when applied to the skin, emphasizing the need for caution in its use.
Octinoxate, commonly found in various cosmetic and personal care products such as hair color products, sunscreen, lipstick, and skin creams, is an endocrine disruptor that mimics estrogen and can affect thyroid function. It has been detected in human urine, blood, and breast milk, indicating systemic exposure. Octinoxate's potential health concerns include its impact on cell proliferation in response to estrogen exposure, disruptions in thyroid hormones, alterations in reproductive systems, and adverse effects on the development of male and female fetuses, as well as their offspring.
2-Hydroxy-4-methoxybenzophenone (Benzophenone-3; BP-3) is a compound used as a UV absorber and stabilizer in plastics, paints, and sunscreens. Human studies have found photosensitivity to it, while non-human animal studies have found that high concentrations contribute to changes in liver weight and disruptions to reproductive parameters in mice and rats. It is identified as an endocrine-disrupting chemical and can affect the behavior of certain fish species. Despite this, it did not induce gene mutations in tests with the bacterium Salmonella typhimurium.
2-Phenoxyethanol is a hazardous substance toxic by all routes of exposure, and is used widely in products like cosmetics, soaps, and inks, among others. The effects of exposure to this faintly aromatic, colorless, oily liquid can include eye irritation, headaches, tremors, and CNS depression. It's crucial to rinse exposed eyes with tepid water for at least 15 minutes and to wash exposed skin thoroughly with soap and water in case of contact. The substance requires preheating before ignition can occur, and if involved in a fire, gentle water spray can extinguish the fire by inducing frothing.
Phthalates, linked to endocrine disruption, reproductive toxicity, and cancer, are banned in the European Union but remain prevalent in U.S. cosmetics. They are widely used in personal care products, such as nail polish, fragrances, and eyelash glue and other products. A significant loophole allows phthalates to be added to fragrances without disclosure. Health concerns include endocrine disruption, developmental and reproductive toxicity, and potential carcinogenicity.
Campaign for Safe Cosmetics: Phthalates, Product Profile: Hand Sanitizer, Phthalates in Cosmetics, Phthalates in cosmetic and personal care products: concentrations and possible dermal exposure, A Survey of Phthalates and Parabens in Personal Care Products from the United States and Its Implications for Human Exposure, Phthalates Factsheet, BPA and Phthalates: Chemicals found in our homes
Acrylamide is a man-made white crystalline solid primarily used in the production of polymers and copolymers. In humans, it is toxic and irritates the skin and mucous membranes, and can affect the central, peripheral, and autonomic nervous systems leading to symptoms like memory difficulties, confusion, slurred speech, and excessive sweating. It may cause peripheral neuropathy, resulting in loss of sensation and muscle wasting. Recovery after exposure can take months to years. Animal studies indicate acrylamide accumulates in the nervous system, liver, kidney, and male reproductive system, causing degenerative changes. It might disrupt metabolism, induce oxidative stress, cause chromosomal aberrations, and tumor initiation. There is no evidence of teratogenic effects in humans or causing cancer. It has also shown genotoxic effects in some aquatic species like C. Auratus and mussels.
Ethylene is a colorless gas used in various applications, from welding to manufacturing plastics and accelerating fruit ripening. Human exposure to high concentrations can cause memory disturbances, loss of consciousness, and even death by suffocation, as it affects the respiratory center in the brain. Chronic exposure has been associated with sensory and cardiovascular alterations. Animal studies show that prolonged exposure can cause decreased food intake, changes in blood cells, and hypertension, but no substantial changes in behavior, body weight, or organ structure were observed. It is metabolized into carcinogenic and mutagenic ethylene oxide in some species, but no significant increase in micronucleated polychromatic erythrocytes was found in rodents exposed to ethylene.
Ingestion or dermal absorption of the chemical at more than 800-1000 mg/kg/day can lead to central nervous system depression and liver and kidney changes in animals, despite there being no significant developmental toxicity. The chemical acts as an eye irritant; however, it is poorly absorbed through the skin. Unanticipated side effects are unlikely unless there is exposure to mists of heated liquid. Notably, animal feeding studies have shown that the chemical could damage the CNS, liver, kidneys, red blood cells, and the reproductive system.
Polyquaternium, modified polymers through quaternization are known for skin toxicity and allergenicity. Prolonged exposure, especially for hairdressers and janitors, may pose risks. It's found in various products, including hair conditioners, creams, and household cleaning items. Concerns include skin irritation, formaldehyde release, and contact dermatitis. Regulations in the EU limit Quaternium-15 to 0.2% in cosmetics, while the US lacks specific regulations.
Polytetrafluoroethylene (PTFE), commonly found in cosmetics, particularly anti-aging products, is favored for its smooth finish. PTFE is trademarked as Teflon® and is also used in non-stick cookware. However, concerns have arisen due to its fluorinated nature, linking it and similar compounds to delayed menstruation, delayed breast development, and cancer. These ingredients can be found in various cosmetic products like foundation, pressed powder, bronzer, blush, eye shadow, mascara, shave gel, lip balm, and anti-aging lotion.
Oral administration of high doses in adults causes ciricrhosis, hemorrhage, anorexia, jaundice, and dermatitis. The use of this substance is contraindicated in pregnancy at doses larger than the FDA recommend daily allowance. Ingesting 25,000 IU/d over a period of 2-3 weeks may result in toxicity, symptoms of which include liver injury and increased intracranial pressure, leading to blurred vision, headaches, and changes to mental status. The substance is also found to be an irritant and harmful if ingested, with teratogenic effects observed in experimental animals.
Styrene is a colorless to yellowish, oily liquid used mainly in plastic, synthetic rubber, and resin production but also as a flavoring agent. Acute human exposure can cause irritation, drowsiness, and vertigo, with skin blistering and dermatitis resulting from long-term contact. It has been linked to increased rates of certain types of cancer, liver effects, and problems with the reproductive system. Animal studies have similarly shown irritation, central nervous system effects, and links to cancers. Styrene's endocrine disruptor activity appears negligible in humans and other vertebrates, but there is evidence of impact in certain aquatic species.
The study on 1,576 U.S. workers exposed to TiO2 for over a year from 1956 to 1985 showed no increase in lung cancer or chronic respiratory disease, and no cases of pulmonary fibrosis. Cases of pulmonary fibrosis related to TiO2 exposure have been reported, possibly due to silica contamination. There are no listed effects for short-term or long-term exposure. Although NIOSH recognises ultrafine TiO2 as a potential occupational carcinogen, data is insufficient to classify fine TiO2 similarly. Epidemiological studies do not provide clear evidence of lung cancer risks from TiO2 dust exposure.
Benzalkonium chloride (BAC) is an organic salt known for its robust antimicrobial properties, effective against various bacteria, viruses, and fungi. It is frequently employed in healthcare settings like hospitals for disinfecting instruments and surfaces. Additionally, BAC is present in many consumer items, including hand sanitizers, wipes, eye solutions, nasal sprays, and personal care products such as soaps and shampoos. Although typically safe when used as instructed, BAC can lead to skin and eye irritation, particularly at elevated concentrations.
Ecological Risk Analysis for Benzalkonium Chloride, Benzethonium Chloride, and Chloroxylenol in US Disinfecting and Sanitizing Products, Evaluation of pulmonary toxicity of benzalkonium chloride and triethylene glycol mixtures using in vitro and in vivo systems, Quaternary Ammonium Compounds in Cleaning Products, Impact of benzalkonium chloride, benzethonium chloride and chloroxylenol on bacterial antimicrobial resistance, Benzalkonium Chloride, SpecialChem: benzalkonium-chloride, Impact of benzalkonium chloride, benzethonium chloride and chloroxylenol on bacterial antimicrobial resistance
Diethanolamine is a chemical found in various consumer products like shampoos, cosmetics, and pharmaceuticals. Acute exposure in humans can result in irritation of the nose, throat, and skin. However, no detailed data is available on its chronic, reproductive, developmental or carcinogenic effects on humans. Studies on animals reveal that acute oral exposure can influence the liver, blood, kidney, and central nervous system, while dermal exposure has been connected with an increased incidence of liver and kidney tumors in mice. Production of first-degree burns, skin irritation, occupational asthma, kidney, and liver injury risk, and potential skin sensitization are some other adverse effects associated with diethanolamine.
Chemical Safety Facts: Ethanolamines, NTP Toxicology and Carcinogenesis Studies of Diethanolamine, California Environmental Protection Agency: Diethanolamine , International Agency for Research on Cancer: Diethanolamine, Initial List of Hazardous Air Pollutants with Modifications, What is the Toxics Release Inventory?, OPINION CONCERNING DIALKYL- AND DIALKANOLAMINES AND THEIR SALTS IN COSMETIC PRODUCTS, Ethanolamine Compounds (MEA, DEA, TEA And Others), WHAT ARE ETHANOLAMINE COMPOUNDS (DEA, MEA, OR TEA): CHEMICAL FREE LIVING, The Dirty Dozen: DEA-related ingredients, FDA: Diethanolamine, Chemical Profile: Diethanolamine ,
Formaldehyde is a colorless, flammable gas with a pungent smell that's naturally produced in small quantities in human bodies and is also known as methanal amongst other names. It's used in the production of various items such as fertilizers, paper, plywood, and urea-formaldehyde resins as well as in some foods and household products like antiseptics, medicines, and cosmetics. Exposure to formaldehyde, which can occur through breathing contaminated indoor air, tobacco smoke, or ambient urban air can lead to respiratory symptoms, irritation of the eyes, nose and throat and has been linked to lung and nasopharyngeal cancer as well as leukemia. The EPA considers formaldehyde a probable human carcinogen (Group B1) and inhaling it can cause bronchospasm and pulmonary edema. Commercially, it's sold as formalin in solutions of 37%, 44%, or 50% and long-term exposure can cause first-degree burns, skin sensitization, squamous cell nasal cancer, and chronic pulmonary obstruction.
Formaldehyde and Cancer Risk, Cleaning Products & Indoor Air Quality, No More Toxic Tub, Campaign for Safe Cosmetics: Preservatives, Campaign for Safe Cosmetics: Formaldehyde And Formaldehyde-Releasing Preservatives, Formaldehyde may be found in cosmetic products even when unlabelled, Formaldehyde Found in Popular American Beauty Products, Hair Salons - Formaldehyde in Your Products, Formaldehyde in cosmetic products
Quaternium-15 is a preservative commonly used in cosmetics which is known to significantly contribute to allergic contact dermatitis in users. This condition has been reported in various professions, including hairdressers, machine maintenance engineers at a chicken processing plant, and photocopy workers. Notably, Quaternium-15, as a formaldehyde releaser, increases dermatitis risk. However, rinse-off products typically pose a lower risk of resulting in allergic contact dermatitis.