Best Non-Toxic Floor Cleaner in 2025
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Welpr Approved cleaning products are always free from:
- Harsh disinfectants and irritants: bleach, ammonia, sulfates, and quats
- Endocrine disruptors and preservatives: phthalates, parabens, BHA/BHT, triclosan
- Unnecessary additives: optical brighteners, artificial dyes, and synthetic fragrance (unless certified safe)
- Undisclosed or hidden ingredients
Find Non-Toxic Floor Cleaner
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User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Natural Multi-Surface Cleaner, Green Tea & Lime - Puracy
Product Details
- Non-toxic and safe for children, pets, and all household surfaces.
- Uses a plant-based formula developed by doctors for effective cleaning.
- Provides residue-free and sparkling results on a variety of surfaces.
- Eco-friendly with a 90% reduction in plastic packaging.
- Biodegradable, cruelty-free, and made in the USA.
Pros & Cons
Pros
- All-natural formula without harsh chemicals ensures a safer clean for health-conscious individuals.
- Versatile cleaner suitable for a wide range of surfaces, from countertops to bathroom tiles.
- Subtle, pleasant scent enhances the cleaning experience without being overpowering.
- Cleans effectively, leaving surfaces sparkling with minimal effort.
- Eco-friendly and great for those with chemical sensitivities, making it an environmentally responsible choice.
Cons
- Some users mention issues with the spray nozzle, requiring alternative spray bottles for convenience.
- A few users note that it may not tackle heavy-duty grime as effectively as chemical-based cleaners.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Purified Water, Decyl Glucoside (Sugar-Based Cleanser), C6-C12 Alcohol Ethoxylate (Sugar-Based Cleanser), C12-C15 Alcohol Ethoxylate (Plant-Based Cleanser), C9-C11 Alcohol Ethoxylate (Plant-Based Cleanser), Citric Acid (Plant-Based pH Neutralizer), Sodium Citrate (Plant-Based pH Neutralizer), Natural Green Tea & Lime Botanical Extracts, Benzisothiazolinone (Biodegradable Preservative)
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User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Hardwood Floor Cleaner, Bright Lemon - Aunt Fannie's
Product Details
- Leaves floors sparkling without the use of harsh chemicals.
- Safe for all hardwood floors including solid, engineered, bamboo, and laminated floors.
- Requires no rinsing, leaving no residue behind.
- Safe to use around kids and pets, dermatologist tested and hypoallergenic.
- Features a refreshing, bright essential oil lemon scent.
Pros & Cons
Pros
- Low-tox formula, safe for children and pets.
- Leaves floors clean with no sticky residue.
- Subtle, pleasant scent without overpowering chemicals.
- Concentrated formula, requiring minimal use for great results.
- Suitable for various surfaces without leaving streaks.
Cons
- Some users looking for a high gloss may not find the desired shine.
- Using in mopping machines may require thorough cleaning afterward to avoid odor buildup.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Sugar Surfactant (Caprylyl/Myristyl Glucoside), Orange Peel Extract, Litsea Cubeba Fruit Oil, Spearmint Oil, Peppermint Oil, Lemon Peel Oil, Sodium Citrate, Citric Acid, Sodium Benzoate, Potassium Cocoate
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Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Floor Surface Cleaner, Citrus Zest - Attitude
Product Details
- Certified by the Environmental Working Group, ensuring strict health and safety standards.
- Formulated with 94% natural ingredients, providing an effective clean without the need for rinsing.
- Free from harmful substances like phthalates, ammonia, bleach, and colorants.
- Works seamlessly on a variety of surfaces, including tile, ceramic, and treated wood.
- Vegan and cruelty-free, reflecting a commitment to animal welfare.
Pros & Cons
Pros
- Leaves floors sparkling clean and shiny without streaks.
- Features a pleasant, not overpowering citrus scent.
- Eco-friendly and non-toxic, safe for kids and pets.
- Economical as a little product goes a long way.
- Easy to use and mix with water for effective cleaning.
Cons
- Some users might find the scent not as strong as expected.
- A few users noted it could leave a slight stickiness if not diluted properly.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: <5% Non-Ionic Surfactants (Caprylyl Glucoside, Myristyl Glucoside), Contains Also: Water, Sodium Citrate, Sapindus Mukorossi Fruit Extract (Saponins), Sodium Gluconate, Sodium Carbonate, Tetrasodium Iminodisuccinate, Oleic Acid, Triethyl Citrate, Terpineol Acetate, Terpineol, Tetrahydrolinalool, Fragrance
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Vinegar Floor Cleaner Concentrate, Bright Lemon - Aunt Fannie's
Product Details
- Eliminates dirt, food residue, grease, and grime for a spotless clean.
- Made with natural ingredients and 100% essential oils for a fresh, pleasant scent.
- Free of harsh chemicals, protecting your health and the environment.
- Safe for use around people and pets, offering peace of mind.
- Adapts to a variety of cleaning methods, including mop buckets and spray bottles.
Pros & Cons
Pros
- Featuring natural, eco-friendly ingredients, it's safe for kids and pets.
- The bright lemon scent is refreshing without being overpowering.
- Leaves floors clean, shiny, and streak-free with no sticky residue.
- A little goes a long way, enhancing its longevity and value.
- Versatile for different cleaning methods, from mopping to spot cleaning.
Cons
- Some users may notice a faint vinegar scent that could be off-putting at first.
- A few have experienced residue on certain types of tile floors.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Distilled White Vinegar, Sugar Surfactant (Caprylyl/Myristyl Glucoside), Polyglyceryl-6 Caprylate, Polyglyceryl-4 Caprate, Litsea Cubeba Fruit Oil, Peppermint Oil, Lemon Peel Oil, Orange Peel Oil, Spearmint Oil
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Multi-Purpose Cleaner, Disinfectant & Deodorizer, Unscented - Force Of Nature
Product Details
- Kills 99.9% of germs, viruses, and bacteria using natural ingredients.
- Replaces multiple cleaning products for various surfaces like kitchens, bathrooms, and mirrors.
- No toxic chemicals, fragrances, or dyes, making it safe for families.
- Environmentally friendly by reducing plastic waste with reusable bottles and recyclable capsules.
- No gloves or rinsing needed, ensuring safety for use around babies and pets.
Pros & Cons
Pros
- Non-toxic and safe for children and pets.
- Easily replaces multiple household cleaning products.
- Effective in disinfecting without harsh smells or chemicals.
- Simple to make and use, with easy-to-follow instructions.
- Customer service is responsive and helpful.
Cons
- Some users experienced issues with the spray bottle and machine reliability.
- Must be monitored for expiry as it lasts only 14 days unless preserved properly.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Salt, Vinegar
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Natural Hardwood Floor Cleaner , Fresh Citrus - Begley's
Product Details
- Effectively cleans hardwood floors without harmful fumes, making it safe for your family and pets.
- Delivers streak-free performance with no waxy film or residue, reducing fingerprints and smudges.
- USDA Certified Biobased product, ensuring a safe and eco-friendly cleaning solution.
- Ready-to-use formula with a natural citrus scent for a fresh and clean atmosphere.
- Proudly made in the USA with cruelty-free and plant-derived ingredients.
Pros & Cons
Pros
- Non-toxic and pet-friendly, ideal for households with pets.
- Leaves hardwood floors clean without any residue or streaks.
- Features a light, natural fragrance that's not overwhelming.
- Plant-based formula is eco-conscious and safe for your family.
- Quick-drying and easy to use with a spray bottle.
Cons
- Some users experienced issues with packaging, leading to broken spray bottles.
- A few users with older floors reported a lack of shine.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Specially Denatured Alcohol (SDA) 38B, Decyl Glucoside, Natural Fragrance Blend (From Essential Oils), Phenoxyethanol
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Save 20% on purchases on Rustic Strength.
Floor Cleaner Concentrate, Unscented - Rustic Strength
Product Details
- Cleans sealed floors and hard surfaces with a fast-drying, pH-neutral formula.
- Safe for homes with kids and pets, leaving no toxic residue behind.
- Economical concentrate mixes easily for powerful daily cleaning.
- 100% biodegradable and safe for septic and graywater systems.
- Free from bleach, ammonia, dyes, and other common irritants.
Pros & Cons
Pros
- Cleans floors effectively without harsh or toxic ingredients.
- Non-toxic and environmentally friendly, making it a safer choice for people and pets.
- Available in fresh, natural scents like Pressed Flowers, which users love.
- A great alternative to conventional floor cleaners with questionable ingredients.
Cons
- Some users wish they had purchased a larger size after trying and loving the product.
Ingredients
Ingredients: Charcoal Filtered Deionized Water, Coco-Glucoside, Caprylyl Capryl Glucoside, Alcohol (Ethyl), Sodium Gluconate, Sodium Citrate, Caprylyl Glycol, Phenoxyethanol, Citric Acid
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Wood & Floor Cleaner Concentrate - Mighty Mint
Product Details
- Cleans and conditions hardwood, laminate, and sealed wood floors without toxic residue.
- Made from plant-based ingredients with a natural oil soap formula.
- Compatible with spray mops, standard mops, and other common cleaning tools.
- Concentrated formula makes up to 8 gallons of cleaning solution.
- Safe to use around people and pets when used as directed.
Pros & Cons
Pros
- Cleans hardwood floors effectively without streaks or sticky residue.
- Leaves a fresh, pleasant scent that’s not overpowering.
- Dries quickly and gives floors a natural-looking shine.
- Concentrated formula allows easy dilution based on preference.
- A non-toxic, low-odor alternative to harsh industrial cleaners.
Cons
- One user noted a recent change in consistency, suggesting possible inconsistency between batches.
Ingredients
Ingredients: Water, Glycerin, Polyglyceryl Oleate, Soap (From Plant Based Bean Oils), Peppermint Oil
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Multi-Surface Cleaning Concentrate, Lemongrass - SCD Probiotics
Product Details
- Harnesses the power of active probiotics and enzymes to safely clean hard and porous surfaces like countertops, tiles, and rugs.
- Eco-friendly and safe for use around babies, kids, and pets, with a hypoallergenic lemon scent from organic essential oil.
- No-rinse formula leaves no residue, making cleaning effortless on surfaces like kitchen countertops, bathroom tiles, and yoga mats.
- Ultra-concentrated solution is cost-effective and sustainable, diluting to create two gallons of ready-to-use cleaner.
- Live probiotics continue cleaning for up to 7 days after application, providing a long-lasting and regenerative cleaning solution.
Pros & Cons
Pros
- Cleans effectively on a variety of surfaces, including granite, wood, and cabinet doors.
- Infused with probiotics, promoting a healthier home environment.
- Non-toxic and child-friendly, perfect for families.
- Leaves a pleasant, light lemongrass scent that isn't overpowering.
- Highly concentrated formula, making it long-lasting.
Cons
- Some users may find the lemongrass scent unappealing.
- The bottle could leak during shipping.
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, 13 Probiotics, Beneficial Postbiotics From Fermentation Brew, Lemongrass Essential Oil
Common Harmful Chemicals in Floor Cleaner
Chemical Name
Why it’s harmful
Benzene is a colorless, sweet-smelling, highly flammable liquid that evaporates quickly into the air and slightly dissolves in water. It's a byproduct of both natural processes and human activities, used extensively in the U.S production of other chemicals for plastics, resins, nylon, rubbers, lubricants, dyes, detergents, drugs, and pesticides. Present in crude oil, gasoline, and cigarette smoke, benzene is also released into the air from burning coal, oil, gasoline stations, and vehicle exhaust. Short-term exposure may cause drowsiness, dizziness, and irritation, while long-term exposure leads to blood disorders, reproductive effects, and even leukemia. Benzene has been classified by EPA as a known human carcinogen, and regulations apply to various industry sectors with potentially high exposure risks.
Tripropylene Glycol Monomethyl Ether may cause mild and transient eye irritation, and it could have anesthetic effects. Continuous or repeated overexposure may lead to kidney and neural injury. The chemical doesn't show any hematotoxicity, but excessive exposure might result in narcotic or anesthetic effects.
Sodium Dichloroisocyanurate is toxic upon ingestion and act as a strong oxidizer, posing a fire hazard when exposed to organic materials. It may react violently with combustible substances and decompose due to heat or water, releasing toxic gases such as chlorine. It can cause irritation to the skin, eyes and respiratory tract, and prolonged exposure can result in corrosive skin burns. Inhalation of high concentrations can lead to acute pulmonary edema. It may also explode from shock, friction, or other ignition sources, and can cause fires upon contact with combustible materials.
Nonylphenol ethoxylate, commonly found in cleaning products, has been linked to allergic contact dermatitis among workers. It is a strong eye irritant, causing mild to severe eye irritation, possible corneal injury, and mild skin irritation. Inhalation can be harmful. It has been shown to cause changes in liver functions and have demonstrated effects on the liver, kidney, and fetus at doses that are toxic to mothers (maternally toxic) in non-mammalian species. Despite these effects, there is no reported teratogenicity, carcinogenicity, or skin sensitization associated with nonylphenol ethoxylate in experimental animals and human studies.
2-Aminoethanol is a colorless, viscous liquid that, despite not being registered for pesticide use in the U.S, holds vast potential in a variety of applications. It can be used in cutting fluids, production of soaps, surfactants, salts, corrosion control inhibitors, pharmaceuticals, and even in protective topical solutions against chemical warfare agents. Used as a pharmaceutical adjuvant, 2-Aminoethanol is effective as a solvent for fats and oils and in creating emulsion formulas like lotions and creams. However, it poses health risks, as a 5.9% concentration can irritate human skin and inhalation may cause allergic reactions, liver damage, and liver symptoms.
Diethanolamine is a chemical found in various consumer products like shampoos, cosmetics, and pharmaceuticals. Acute exposure in humans can result in irritation of the nose, throat, and skin. However, no detailed data is available on its chronic, reproductive, developmental or carcinogenic effects on humans. Studies on animals reveal that acute oral exposure can influence the liver, blood, kidney, and central nervous system, while dermal exposure has been connected with an increased incidence of liver and kidney tumors in mice. Production of first-degree burns, skin irritation, occupational asthma, kidney, and liver injury risk, and potential skin sensitization are some other adverse effects associated with diethanolamine.
Chemical Safety Facts: Ethanolamines, NTP Toxicology and Carcinogenesis Studies of Diethanolamine, California Environmental Protection Agency: Diethanolamine , International Agency for Research on Cancer: Diethanolamine, Initial List of Hazardous Air Pollutants with Modifications, What is the Toxics Release Inventory?, OPINION CONCERNING DIALKYL- AND DIALKANOLAMINES AND THEIR SALTS IN COSMETIC PRODUCTS, Ethanolamine Compounds (MEA, DEA, TEA And Others), WHAT ARE ETHANOLAMINE COMPOUNDS (DEA, MEA, OR TEA): CHEMICAL FREE LIVING, The Dirty Dozen: DEA-related ingredients, FDA: Diethanolamine, Chemical Profile: Diethanolamine ,
Triethanolamine appears to cause occupational asthma and allergic contact dermatitis in machinists and photographers, as well as liver and kidney damage in animals with high-dose feeding. It's noted to be an irritant to the skin, eyes, and respiratory tract, with potential to cause skin sensitization, though the rate of skin sensitization in humans is low. Triethanolamine has low acute toxicity, with median oral LD50 values of 4,190-11,260 mg/kg in rats and 5,300-8,000 mg/kg in guinea pigs, and a median dermal LD50 greater than 2,000 mg/kg in rabbits. Triethanolamine is not carcinogenic, developmental toxicant, or toxic to the reproductive system. However, chronic exposure may lead to liver and kidney damage.
Safety assessment of triethanolamine and triethanolamine-containing ingredients as used in cosmetics, Toxicology of mono-, di-, and triethanolamine, Campaign for Safe Cosmetics: Ethanolamine Compounds (MEA, DEA, TEA And Others), The Dirty Dozen: DEA-related ingredients, Chemical Profile, Special Chem, Safety assessment of triethanolamine and triethanolamine-containing ingredients as used in cosmetics
Perfluorooctanoic acid (PFOA) is primarily used to create salts that aid in the processing of producing fluoropolymers and fluoroelastomers. It also acts as a surfactant in firefighting foams, an intermediate in creating fluoroacrylic esters, and a crucial aspect in manufacturing Teflon and similar chemicals. However, exposure to PFOA can lead to adverse health effects, including alterations in thyroid hormone levels, lower fertility, an increased risk of cerebrovascular disease, higher cholesterol and triglyceride levels, a possible link to ADHD, smaller abdominal circumference and birth length in infants, an increased risk of common cold and gastroenteritis in children, and potentially prostate cancer mortality. Studies on animals have indicated possible liver and brain dysfunction, carcinogenicity, and reproductive and developmental toxicity. Ecotoxicity studies found alterations in genes linked to lipid metabolism, hormone action, immune responses, and mitochondrial functions in rare minnows exposed to PFOA.
Perfluoroalkyls are synthetic chemicals known for their ability to resist oil, grease, and water, primarily used in surface protection products and fire-fighting foams. The two most abundant perfluoroalkyls are perflurooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS). Studies have observed liver enlargement and elevated cholesterol in animals given high doses, and the presence of PFOS in various populations has raised environmental and health concerns, leading to the phase-out of some PFOS-based chemicals. Tests have shown a range of health effects in animals, including eye irritation, liver changes, teratogenic effects, and more, with no evidence of mutagenicity. However, no substantial link has been found between PFAS concentrations and increased cardiometabolic risk measures in human studies, and there are no known health effects from exposure when used as intended.
Isothiazolinones are preservatives known to cause allergic contact dermatitis, primarily in workers involved in manufacturing industries like paint, paper, rubber, and air fresheners. Additionally, there's a reported case of occupational asthma from exposure to this chemical among workers.
Acetone is a colorless, flammable liquid that dissolves in water and has a distinct smell and taste. It is also known as dimethyl ketone, 2-propanone, and beta-ketopropane. This manufactured chemical, which is used to create plastic, fibers, drugs, and other chemicals, can also be found in the environment in plants, trees, volcanic gases, forest fires, vehicle exhaust, tobacco smoke, and landfill sites, with industrial processes contributing more to its presence than natural ones. Acetone can be harmful if absorbed through the skin or inhaled, potentially causing irritation to the skin and respiratory tract, as well as adverse effects on the central nervous system (CNS), liver, and kidneys. The allowable exposure limit is set based on its potential to cause eye and upper respiratory irritation and CNS impairment.
Diethylene Glycol Monoethyl Ether, when administered orally or through the skin in doses exceeding 800-1000 mg/kg/day, can cause central nervous system depression and changes to the liver and kidneys in animals. However, it doesn't exhibit significant developmental toxicity at these levels. The chemical is not expected to have adverse effects unless workers are exposed to its heated liquid mists. It is an eye irritant and provokes harm to the central nervous system, liver, kidneys, red blood cells, and reproductive system in animal feeding studies. Despite these potential harms, it is poorly absorbed through the skin.
DMDM hydantoin is a substance used in cosmetics that has the potential to cause allergic contact dermatitis, although rinse-off products generally have a low risk. According to various reports, skin sensitization patch testing has yielded positive results.
Laureth-7, a surfactant derived from lauryl alcohol sourced from coconut or palm oil, is commonly used in personal care and household products, especially laundry detergents. In detergents, it functions by reducing surface tension between water and soil, aiding in the removal of dirt, stains, and oils from fabrics. This ingredient belongs to the Polyethylene Glycols (PEGs) family, which is found in various consumer goods. Despite past contamination concerns, modern manufacturing processes have addressed and eliminated these issues. Although PEGs are not used in certain personal care products, their inclusion in machine detergents is deemed acceptable since they don't directly touch the skin.
d-Limonene is a liquid with a lemon-like smell, often used as a solvent to substitute for more volatile and toxic organic solvents. When it comes into contact with air, it can oxidize, and this oxidized form is a known skin sensitizer, capable of irritating skin and eyes. The combination of d-limonene and l-limonene is known as limonene or dipentene. The estimated lethal dose for humans is between 0.5 to 5 g/kg, and studies have shown that it can cause diarrhea and liver effects when ingested in high doses.
Linalool is a naturally occurring terpene alcohol found in many flowers and spice plants, consisting of two enantiomers. It is widely used in commercial products for its pleasant floral and spicy scent, serving as a key ingredient in soaps, fragrances, food flavors, household products, and insecticides. In plants, linalool functions as a metabolite, volatile oil component, antimicrobial agent, and aroma compound. Acute exposure to linalool can lead to central depressive effects with symptoms such as ataxia, reduced motor activity, and respiratory disturbances. Additionally, inhalation, oral intake, or skin absorption can result in irritation, pain, and allergic reactions.
5-chloro-2-methyl-4-isothiazolin-3-one (CMI) is a compound frequently used as a preservative in cosmetics, hygiene products, and other industrial applications such as hydraulic fracturing fluids. It can also be deployed as a pesticide in the U.S, pending regulatory approval. CMI, which is often used in combination with 2-methyl-4-isothiazolin-3-one (MI), can cause contact dermatitis in humans. Various animal studies have shown that a high exposure to a CMIT/MIT mixture can cause alterations in rats' liver function. The production and use of CMI in a range of products mean it can be release into the environment, with some susceptibility to degradation through photolysis in sunlight. Its mobility in soil is high but volatilization from soil or water surfaces is not expected to be significant. Occupational and general exposure to CMI can occur especially through inhalation and dermal contact with CMI-containing products.
Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout, Methylisothiazolinone toxicity and inhibition of wound healing and regeneration in planaria, Methylchloroisothiazolinone and/or methylisothiazolinone in cosmetic products, Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles, Methylisothiazolinone and isothiazolinone allergy, Analysis of isothiazolinones in environmental waters by gas chromatography–mass spectrometry, Methylisothiazolinone induces apoptotic cell death via matrix metalloproteinase activation in human bronchial epithelial cells, EU REGULATIONS , Methylisothiazolinone contact allergy: a review, Effects of methylisothiazolinone and octylisothiazolinone on development and thyroid endocrine system in zebrafish larvae, Two Cases of Chloromethylisothiazolinone and Methylisothiazolinone-associated Toxic Lung Injury, An update of the risk assessment for methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) with focus on rinse-off products, Effects of a mixture of chloromethylisothiazolinone and methylisothiazolinone on peripheral airway dysfunction in children, Isothiazolinone preservative: cause of a continuing epidemic of cosmetic dermatitis, Campaign for Safe Cosmetics: Methylisothiazolinone and Methylchloroisothiazolinone
Sodium Cumenesulfonate is a mild eye irritants that can be significantly absorbed upon ingestion but not after skin application. It has not shown skin sensitization in animal tests but have caused acute toxicity symptoms such as decreased activity, prostration, increased saliva production, diarrhea, and liver congestion. Furthermore, sodium cumenesulfonate has not demonstrated carcinogenic effects in dermal exposure studies.
Trideceth-3 is a polyethylene glycol ether of Tridecyl Alcohol used in formulations for its emulsifying and surfactant properties. However, data from the European Union Ecolabel program indicates that this substance possesses high chronic toxicity and very high acute toxicity to aquatic life. Despite these environmental concerns, the Cosmetic Ingredient Review panel has determined Trideceth-3 to be safe when formulated to be non-irritating.
Trideceth-4 is a water-soluble compound with notable wetting, permeability, and emulsifying properties. It enhances the effectiveness of certain silicone oils and is used in various applications including metal processing aids, detergents, and household cleaning agents. However, it can be harmful if ingested and is known to cause serious eye damage, skin irritation, and eye irritation, as indicated by the European Chemicals Agency (ECHA). Despite these concerns, the Cosmetic Ingredient Review panel has determined it to be safe when formulated to be non-irritating.